Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue 5GP A 600 |
| Chain | Residue |
| A | SER74 |
| A | ASP367 |
| A | GLY369 |
| A | MET388 |
| A | GLY390 |
| A | GLY391 |
| A | TYR414 |
| A | GLY416 |
| A | MET417 |
| A | GLY418 |
| A | GLN448 |
| A | MET76 |
| A | GLY449 |
| A | GOL603 |
| A | HOH729 |
| A | HOH766 |
| A | HOH769 |
| A | HOH807 |
| A | HOH809 |
| A | HOH872 |
| A | ASN306 |
| A | ARG325 |
| A | GLY331 |
| A | SER332 |
| A | ILE333 |
| A | CYS334 |
| A | THR336 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 5GP A 601 |
| Chain | Residue |
| A | ILE48 |
| A | PHE50 |
| A | PRO51 |
| A | SER52 |
| A | SER283 |
| A | VAL284 |
| A | PHE285 |
| A | HIS473 |
| A | GLN476 |
| A | HOH718 |
| A | HOH885 |
| A | HOH911 |
| A | HOH945 |
| B | GLU295 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue K A 602 |
| Chain | Residue |
| A | GLY329 |
| A | GLY331 |
| A | CYS334 |
| A | GLU507 |
| A | GLY508 |
| A | GLY509 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 603 |
| Chain | Residue |
| A | ASP277 |
| A | SER278 |
| A | SER279 |
| A | ASN306 |
| A | MET417 |
| A | 5GP600 |
| A | HOH715 |
| A | HOH951 |
| site_id | AC5 |
| Number of Residues | 27 |
| Details | binding site for residue 5GP B 600 |
| Chain | Residue |
| B | SER74 |
| B | MET76 |
| B | ASN306 |
| B | ARG325 |
| B | GLY331 |
| B | SER332 |
| B | ILE333 |
| B | CYS334 |
| B | THR336 |
| B | ASP367 |
| B | GLY369 |
| B | MET388 |
| B | GLY390 |
| B | GLY391 |
| B | TYR414 |
| B | GLY416 |
| B | MET417 |
| B | GLY418 |
| B | GLN448 |
| B | GLY449 |
| B | GOL603 |
| B | HOH733 |
| B | HOH770 |
| B | HOH804 |
| B | HOH809 |
| B | HOH810 |
| B | HOH857 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue 5GP B 601 |
| Chain | Residue |
| B | ILE48 |
| B | PHE50 |
| B | PRO51 |
| B | SER52 |
| B | SER283 |
| B | VAL284 |
| B | PHE285 |
| B | HIS473 |
| B | GLN476 |
| B | HOH745 |
| B | HOH760 |
| B | HOH780 |
| B | HOH863 |
| B | HOH869 |
| B | HOH916 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue K B 602 |
| Chain | Residue |
| B | CYS334 |
| B | GLU507 |
| B | GLY508 |
| B | GLY509 |
| B | GLY329 |
| B | GLY331 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 603 |
| Chain | Residue |
| B | ASP277 |
| B | SER278 |
| B | ASN306 |
| B | MET417 |
| B | 5GP600 |
| B | HOH940 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. LRIGMGsGSICiT |
| Chain | Residue | Details |
| A | LEU324-THR336 | |
4Z0G
