4YW4

Streptococcus pneumoniae sialidase NanC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004308	molecular_function	exo-alpha-sialidase activity
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006689	biological_process	ganglioside catabolic process
A	0009313	biological_process	oligosaccharide catabolic process
A	0016020	cellular_component	membrane
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0052794	molecular_function	exo-alpha-(2->3)-sialidase activity
A	0052795	molecular_function	exo-alpha-(2->6)-sialidase activity
A	0052796	molecular_function	exo-alpha-(2->8)-sialidase activity
B	0004308	molecular_function	exo-alpha-sialidase activity
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0006689	biological_process	ganglioside catabolic process
B	0009313	biological_process	oligosaccharide catabolic process
B	0016020	cellular_component	membrane
B	0043231	cellular_component	intracellular membrane-bounded organelle
B	0052794	molecular_function	exo-alpha-(2->3)-sialidase activity
B	0052795	molecular_function	exo-alpha-(2->6)-sialidase activity
B	0052796	molecular_function	exo-alpha-(2->8)-sialidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue PO4 A 801

Chain	Residue
A	ARG290
A	ASP315
A	ARG600
A	ARG662
A	TYR695
A	HOH1062

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site_id	AC2
Number of Residues	9
Details	binding site for residue GOL A 802

Chain	Residue
A	ALA205
A	ASN206
A	THR208
A	LYS724
A	ASN725
A	HOH905
A	ARG173
A	SER176
A	TRP178

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site_id	AC3
Number of Residues	6
Details	binding site for residue PO4 B 801

Chain	Residue
B	ARG290
B	ASP315
B	ARG600
B	ARG662
B	TYR695
B	HOH1033

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site_id	AC4
Number of Residues	6
Details	binding site for residue GOL B 802

Chain	Residue
B	LYS209
B	VAL211
B	GLU212
B	GLU352
B	LYS724
B	HOH904

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