4YRS

Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with N-(quinolin-3-yl)propanamide (Chem 1698)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004821	molecular_function	histidine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006427	biological_process	histidyl-tRNA aminoacylation
A	0016874	molecular_function	ligase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue HIS A 501

Chain	Residue
A	GLU126
A	PHE360
A	GLY361
A	HOH601
A	HOH606
A	THR128
A	GLN170
A	ASP174
A	LEU316
A	TYR318
A	TYR319
A	TYR342
A	GLY359

---

site_id	AC2
Number of Residues	8
Details	binding site for residue 4JS A 502

Chain	Residue
A	PRO125
A	CYS154
A	TRP155
A	ARG156
A	ARG165
A	GLU167
A	HIS168
A	CYS365

---