Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4YRN

Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 6-bromopyridin-3-amine (Chem 475)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004821molecular_functionhistidine-tRNA ligase activity
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0006427biological_processhistidyl-tRNA aminoacylation
A0016874molecular_functionligase activity
B0004821molecular_functionhistidine-tRNA ligase activity
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0006427biological_processhistidyl-tRNA aminoacylation
B0016874molecular_functionligase activity
Functional Information from PDB Data
site_idAC1
Number of Residues16
Detailsbinding site for residue HIS A 501
ChainResidue
AGLU126
AGLY359
APHE360
AGLY361
AHOH619
AHOH648
AHOH679
AHOH687
ATHR128
AGLN170
AASN172
AASP174
ALEU316
ATYR318
ATYR319
ATYR342

site_idAC2
Number of Residues7
Detailsbinding site for residue 4JN A 502
ChainResidue
APRO125
ACYS154
ATRP155
AARG156
AGLU167
AHIS168
AHOH697

site_idAC3
Number of Residues3
Detailsbinding site for residue DMS A 503
ChainResidue
ATRP193
AARG196
ASER197

site_idAC4
Number of Residues7
Detailsbinding site for residue DMS A 504
ChainResidue
AGLU96
ALEU97
AILE99
AARG100
ATYR349
AHOH617
AHOH671

site_idAC5
Number of Residues4
Detailsbinding site for residue EDO A 505
ChainResidue
ATHR115
AGLY117
BTYR157
BARG166

site_idAC6
Number of Residues5
Detailsbinding site for residue SO4 A 506
ChainResidue
AHIS168
AGLY363
AASP364
ACYS365
AVAL366

site_idAC7
Number of Residues5
Detailsbinding site for residue SO4 A 507
ChainResidue
AARG196
ASER201
ASER202
ATRP305
AHOH607

site_idAC8
Number of Residues5
Detailsbinding site for residue SO4 A 508
ChainResidue
AARG69
AHIS76
AHOH606
AHOH674
BARG69

site_idAC9
Number of Residues17
Detailsbinding site for residue HIS B 501
ChainResidue
BGLU126
BTHR128
BGLN170
BASN172
BASP174
BLEU316
BTYR318
BTYR319
BTYR342
BGLY359
BPHE360
BGLY361
BHOH620
BHOH660
BHOH670
BHOH678
BHOH688

site_idAD1
Number of Residues6
Detailsbinding site for residue 4JN B 502
ChainResidue
BPRO125
BCYS154
BTRP155
BARG156
BGLU167
BHIS168

site_idAD2
Number of Residues3
Detailsbinding site for residue DMS B 503
ChainResidue
BTRP193
BARG196
BSER197

site_idAD3
Number of Residues4
Detailsbinding site for residue DMS B 504
ChainResidue
BLEU97
BARG100
BTYR349
BHOH609

site_idAD4
Number of Residues5
Detailsbinding site for residue DMS B 505
ChainResidue
AGLN250
AVAL253
ALEU254
BPRO473
BARG476

site_idAD5
Number of Residues4
Detailsbinding site for residue EDO B 506
ChainResidue
ATYR157
AARG166
BTHR115
BGLY117

site_idAD6
Number of Residues4
Detailsbinding site for residue EDO B 507
ChainResidue
BPHE426
BALA437
BGLN451
BLYS453

site_idAD7
Number of Residues5
Detailsbinding site for residue EDO B 508
ChainResidue
BHOH612
BPHE229
BALA317
BTYR319
BASN344

site_idAD8
Number of Residues5
Detailsbinding site for residue EDO B 509
ChainResidue
AVAL472
AARG476
BGLN250
BVAL253
BLEU254

site_idAD9
Number of Residues5
Detailsbinding site for residue SO4 B 510
ChainResidue
BHIS168
BGLY363
BASP364
BCYS365
BVAL366

site_idAE1
Number of Residues4
Detailsbinding site for residue SO4 B 511
ChainResidue
BARG196
BSER201
BSER202
BTRP305

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon