Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 4EK A 801 |
| Chain | Residue |
| A | PHE521 |
| A | GLY667 |
| A | ASP668 |
| A | HOH930 |
| A | ALA542 |
| A | PHE589 |
| A | GLU590 |
| A | MET592 |
| A | ARG654 |
| A | ASN655 |
| A | CYS656 |
| A | LEU657 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 802 |
| Chain | Residue |
| A | THR722 |
| A | LYS725 |
| A | ARG750 |
| A | HOH920 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 803 |
| Chain | Residue |
| A | ARG0 |
| A | HIS503 |
| A | HIS504 |
| A | HOH949 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 804 |
| Chain | Residue |
| A | ARG602 |
| A | ASP607 |
| A | TYR723 |
| A | LYS725 |
| A | HOH973 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 805 |
| Chain | Residue |
| A | GLN633 |
| A | GLY661 |
| A | LEU662 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 806 |
| Chain | Residue |
| A | HIS571 |
| A | SER632 |
| A | GLN633 |
| A | HIS778 |
| A | GLN782 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 807 |
| Chain | Residue |
| A | LYS544 |
| A | GLU560 |
| A | ASP668 |
| A | PHE669 |
| A | GLY670 |
| A | MET671 |
| A | HOH929 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 29 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGKVFlAechnllpeqdkml.....VAVK |
| Chain | Residue | Details |
| A | LEU516-LYS544 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDLATRNCLV |
| Chain | Residue | Details |
| A | PHE646-VAL658 | |
| site_id | PS00239 |
| Number of Residues | 9 |
| Details | RECEPTOR_TYR_KIN_II Receptor tyrosine kinase class II signature. DIYstdYYR |
| Chain | Residue | Details |
| A | ASP674-ARG682 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP650 | |
| Chain | Residue | Details |
| A | LEU516 | |
| A | LYS544 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Interaction with PLCG1 |
| Chain | Residue | Details |
| A | TYR791 | |
| Chain | Residue | Details |
| A | TYR676 | |
| Chain | Residue | Details |
| A | TYR680 | |
| A | TYR681 | |
| Chain | Residue | Details |
| A | TYR791 | |
