Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 4E4 A 1001 |
| Chain | Residue |
| A | HIS57 |
| A | PHE215 |
| A | SO41004 |
| A | HOH1235 |
| A | HOH1242 |
| A | THR96 |
| A | VAL99 |
| A | CYS191 |
| A | GLN192 |
| A | GLY193 |
| A | ASP194 |
| A | SER195 |
| A | SER214 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1002 |
| Chain | Residue |
| A | TYR137 |
| A | GLN156 |
| A | TYR207 |
| A | ACT1010 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 1003 |
| Chain | Residue |
| A | ALA126 |
| A | SER232 |
| A | ALA233 |
| A | TYR234 |
| A | ILE235 |
| A | SER236 |
| A | HOH1198 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1004 |
| Chain | Residue |
| A | PHE215 |
| A | VAL216 |
| A | 4E41001 |
| A | SO41005 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1005 |
| Chain | Residue |
| A | GLU62 |
| A | VAL99 |
| A | THR174 |
| A | SO41004 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 1006 |
| Chain | Residue |
| A | THR146 |
| A | GLN192 |
| A | SER217 |
| A | ARG217 |
| A | GLY219 |
| A | CYS220 |
| A | HOH1193 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 1007 |
| Chain | Residue |
| A | ASN76 |
| A | ASP77 |
| A | GLY78 |
| A | TYR137 |
| A | TYR158 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 1008 |
| Chain | Residue |
| A | ARG36 |
| A | THR64 |
| A | SER173 |
| A | THR174 |
| A | HOH1106 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 1009 |
| Chain | Residue |
| A | ARG65 |
| A | TYR82 |
| A | VAL83 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 1010 |
| Chain | Residue |
| A | SER26 |
| A | TYR207 |
| A | SO41002 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 1011 |
| Chain | Residue |
| A | GLN152 |
| A | THR153 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 1012 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | GLN75 |
| A | GLU80 |
| A | HOH1233 |
| A | HOH1246 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 1013 |
| Chain | Residue |
| A | TRP38 |
| A | HIS40 |
| A | LEU73 |
| A | ASN74 |
| A | HOH1101 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. MTAAHC |
| Chain | Residue | Details |
| A | MET53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SGcqGDSGGPLH |
| Chain | Residue | Details |
| A | SER189-HIS200 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS57 | |
| Chain | Residue | Details |
| A | ASP102 | |
| A | SER195 | |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | GLN75 | |
| A | GLU80 | |
