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4YGX

Crystal Structure of D. melanogaster Ssu72+Symplekin bound to cis peptidomimetic CTD phospho-Ser5 peptide

Functional Information from GO Data
ChainGOidnamespacecontents
B0004721molecular_functionphosphoprotein phosphatase activity
B0004722molecular_functionprotein serine/threonine phosphatase activity
B0005634cellular_componentnucleus
B0005847cellular_componentmRNA cleavage and polyadenylation specificity factor complex
B0006357biological_processregulation of transcription by RNA polymerase II
B0006369biological_processtermination of RNA polymerase II transcription
B0006397biological_processmRNA processing
B0008420molecular_functionRNA polymerase II CTD heptapeptide repeat phosphatase activity
B0016787molecular_functionhydrolase activity
B0016791molecular_functionphosphatase activity
B0031124biological_processmRNA 3'-end processing
D0004721molecular_functionphosphoprotein phosphatase activity
D0004722molecular_functionprotein serine/threonine phosphatase activity
D0005634cellular_componentnucleus
D0005847cellular_componentmRNA cleavage and polyadenylation specificity factor complex
D0006357biological_processregulation of transcription by RNA polymerase II
D0006369biological_processtermination of RNA polymerase II transcription
D0006397biological_processmRNA processing
D0008420molecular_functionRNA polymerase II CTD heptapeptide repeat phosphatase activity
D0016787molecular_functionhydrolase activity
D0016791molecular_functionphosphatase activity
D0031124biological_processmRNA 3'-end processing
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues35
DetailsRepeat: {"description":"HEAT 1","evidences":[{"source":"PubMed","id":"19576221","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues68
DetailsRepeat: {"description":"HEAT 2","evidences":[{"source":"PubMed","id":"19576221","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues84
DetailsRepeat: {"description":"HEAT 3","evidences":[{"source":"PubMed","id":"19576221","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues78
DetailsRepeat: {"description":"HEAT 4","evidences":[{"source":"PubMed","id":"19576221","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues78
DetailsRepeat: {"description":"HEAT 5","evidences":[{"source":"PubMed","id":"19576221","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

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PDB entries from 2025-08-27

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