4YGE
Crystal structure of ERGIC-53/MCFD2, trigonal calcium-bound form 2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0005793 | cellular_component | endoplasmic reticulum-Golgi intermediate compartment |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0012507 | cellular_component | ER to Golgi transport vesicle membrane |
| B | 0015031 | biological_process | protein transport |
| B | 0016192 | biological_process | vesicle-mediated transport |
| B | 0033116 | cellular_component | endoplasmic reticulum-Golgi intermediate compartment membrane |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0016020 | cellular_component | membrane |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0005783 | cellular_component | endoplasmic reticulum |
| D | 0005789 | cellular_component | endoplasmic reticulum membrane |
| D | 0005793 | cellular_component | endoplasmic reticulum-Golgi intermediate compartment |
| D | 0005794 | cellular_component | Golgi apparatus |
| D | 0012507 | cellular_component | ER to Golgi transport vesicle membrane |
| D | 0015031 | biological_process | protein transport |
| D | 0016192 | biological_process | vesicle-mediated transport |
| D | 0033116 | cellular_component | endoplasmic reticulum-Golgi intermediate compartment membrane |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0016020 | cellular_component | membrane |
| F | 0005509 | molecular_function | calcium ion binding |
| F | 0005515 | molecular_function | protein binding |
| F | 0005783 | cellular_component | endoplasmic reticulum |
| F | 0005789 | cellular_component | endoplasmic reticulum membrane |
| F | 0005793 | cellular_component | endoplasmic reticulum-Golgi intermediate compartment |
| F | 0005794 | cellular_component | Golgi apparatus |
| F | 0012507 | cellular_component | ER to Golgi transport vesicle membrane |
| F | 0015031 | biological_process | protein transport |
| F | 0016192 | biological_process | vesicle-mediated transport |
| F | 0033116 | cellular_component | endoplasmic reticulum-Golgi intermediate compartment membrane |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 501 |
| Chain | Residue |
| A | ASP152 |
| A | PHE154 |
| A | ASN156 |
| A | ASP181 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 502 |
| Chain | Residue |
| A | ASP155 |
| A | ASP157 |
| A | ASN161 |
| A | ASN162 |
| A | ASP181 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 503 |
| Chain | Residue |
| A | LYS53 |
| A | GLY54 |
| A | HIS56 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 501 |
| Chain | Residue |
| B | ASP129 |
| B | ASN131 |
| B | ASP133 |
| B | TYR135 |
| B | GLU140 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 502 |
| Chain | Residue |
| B | ASP81 |
| B | ASP83 |
| B | ASN85 |
| B | LEU87 |
| B | GLU92 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 502 |
| Chain | Residue |
| C | LYS53 |
| C | HIS56 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 501 |
| Chain | Residue |
| D | ASP81 |
| D | ASP83 |
| D | ASN85 |
| D | LEU87 |
| D | GLU92 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 502 |
| Chain | Residue |
| D | ASP129 |
| D | ASN131 |
| D | ASP133 |
| D | TYR135 |
| D | GLU140 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL E 501 |
| Chain | Residue |
| E | LYS53 |
| E | GLY54 |
| E | HIS56 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue CA F 501 |
| Chain | Residue |
| F | ASP81 |
| F | ASP83 |
| F | ASN85 |
| F | LEU87 |
| F | GLU92 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CA F 502 |
| Chain | Residue |
| F | ASP129 |
| F | ASN131 |
| F | ASP133 |
| F | TYR135 |
| F | GLU140 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DYDGNNLLDglEL |
| Chain | Residue | Details |
| B | ASP81-LEU93 | |
| B | ASP129-PHE141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 27 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448 |
| Chain | Residue | Details |
| B | ASP81 | |
| D | ASP81 | |
| D | ASP83 | |
| D | ASN85 | |
| D | GLU92 | |
| D | ASP129 | |
| D | ASN131 | |
| D | ASP133 | |
| D | TYR135 | |
| D | GLU140 | |
| F | ASP81 | |
| B | ASP83 | |
| F | ASP83 | |
| F | ASN85 | |
| F | GLU92 | |
| F | ASP129 | |
| F | ASN131 | |
| F | ASP133 | |
| F | TYR135 | |
| F | GLU140 | |
| B | ASN85 | |
| B | GLU92 | |
| B | ASP129 | |
| B | ASN131 | |
| B | ASP133 | |
| B | TYR135 | |
| B | GLU140 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8K5B3 |
| Chain | Residue | Details |
| B | SER106 | |
| E | PHE154 | |
| E | ASN156 | |
| E | ASP181 | |
| D | SER106 | |
| F | SER106 | |
| A | ASP181 | |
| C | ASP152 | |
| C | PHE154 | |
| C | ASN156 | |
| C | ASP181 | |
| E | ASP152 |
