4YGD

Crystal structure of ERGIC-53/MCFD2, monoclinic calcium-bound form 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
B	0005509	molecular_function	calcium ion binding
C	0016020	cellular_component	membrane
D	0005509	molecular_function	calcium ion binding
E	0016020	cellular_component	membrane
F	0005509	molecular_function	calcium ion binding
G	0016020	cellular_component	membrane
H	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CA A 501

Chain	Residue
A	ASP152
A	PHE154
A	ASN156
A	ASP181
A	HOH615

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CA A 502

Chain	Residue
A	ASP181
A	ASP155
A	ASP157
A	ASN161
A	ASN162

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CL A 504

Chain	Residue
A	LYS53
A	GLY54
A	HIS56

---

site_id	AC4
Number of Residues	6
Details	binding site for residue CA B 501

Chain	Residue
B	ASP81
B	ASP83
B	ASN85
B	LEU87
B	GLU92
B	HOH609

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CA B 502

Chain	Residue
B	ASP129
B	ASN131
B	ASP133
B	TYR135
B	GLU140
B	HOH607

---

site_id	AC6
Number of Residues	5
Details	binding site for residue CA C 501

Chain	Residue
C	ASP152
C	PHE154
C	ASN156
C	ASP181
C	HOH646

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CA C 502

Chain	Residue
C	ASP155
C	ASP157
C	ASN161
C	ASN162
C	ASP181

---

site_id	AC8
Number of Residues	5
Details	binding site for residue CA D 501

Chain	Residue
D	ASP81
D	ASP83
D	ASN85
D	LEU87
D	GLU92

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CA D 502

Chain	Residue
D	ASP129
D	ASN131
D	ASP133
D	TYR135
D	GLU140

---

site_id	AD1
Number of Residues	5
Details	binding site for residue CA E 501

Chain	Residue
E	ASP152
E	PHE154
E	ASN156
E	ASP181
E	HOH621

---

site_id	AD2
Number of Residues	5
Details	binding site for residue CA E 502

Chain	Residue
E	ASP155
E	ASP157
E	ASN161
E	ASN162
E	ASP181

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CA F 501

Chain	Residue
F	ASP81
F	ASP83
F	ASN85
F	LEU87
F	GLU92
F	HOH606

---

site_id	AD4
Number of Residues	5
Details	binding site for residue CA F 502

Chain	Residue
F	ASP129
F	ASN131
F	ASP133
F	TYR135
F	GLU140

---

site_id	AD5
Number of Residues	5
Details	binding site for residue CA G 501

Chain	Residue
G	ASP155
G	ASP157
G	ASN161
G	ASN162
G	ASP181

---

site_id	AD6
Number of Residues	4
Details	binding site for residue CA G 502

Chain	Residue
G	ASP152
G	PHE154
G	ASN156
G	ASP181

---

site_id	AD7
Number of Residues	3
Details	binding site for residue CL G 503

Chain	Residue
G	LYS53
G	GLY54
G	HIS56

---

site_id	AD8
Number of Residues	6
Details	binding site for residue CA H 501

Chain	Residue
H	ASP81
H	ASP83
H	ASN85
H	LEU87
H	GLU92
H	HOH606

---

site_id	AD9
Number of Residues	6
Details	binding site for residue CA H 502

Chain	Residue
H	ASP129
H	ASN131
H	ASP133
H	TYR135
H	GLU140
H	HOH605

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DYDGNNLLDglEL

Chain	Residue	Details
B	ASP81-LEU93
B	ASP129-PHE141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448

Chain	Residue	Details
B	ASP81
B	ASP83
B	ASN85
B	GLU92
D	TYR135
D	GLU140
F	ASP81
F	ASP83
F	ASN85
F	GLU92
F	ASP129
F	ASN131
F	ASP133
F	TYR135
F	GLU140
H	ASP81
H	ASP83
H	ASN85
H	GLU92
H	ASP129
H	ASN131
H	ASP133
H	TYR135
H	GLU140
D	GLU92
D	ASP129
D	ASN131
D	ASP133
B	ASP129
B	ASN131
B	ASP133
B	TYR135
B	GLU140
D	ASP81
D	ASP83
D	ASN85

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8K5B3

Chain	Residue	Details
B	SER106
D	SER106
F	SER106
H	SER106
C	ASP152
C	PHE154
C	ASN156
C	ASP181
E	ASP152
E	PHE154
E	ASN156
E	ASP181
G	ASP152
G	PHE154
G	ASN156
G	ASP181

---