4YCA
Evidence of Kinetic Cooperativity in dimeric Ketopantoate Reductase from Staphylococcus aureus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| A | 0015940 | biological_process | pantothenate biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| B | 0015940 | biological_process | pantothenate biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | binding site for residue NDP A 800 |
| Chain | Residue |
| A | GLY9 |
| A | LYS71 |
| A | GLN74 |
| A | ALA77 |
| A | ALA95 |
| A | GLN96 |
| A | ASN97 |
| A | ILE117 |
| A | SER118 |
| A | GLY119 |
| A | LYS121 |
| A | PRO10 |
| A | GLU251 |
| A | HOH946 |
| A | HOH959 |
| A | HOH972 |
| A | HOH999 |
| A | HOH1000 |
| A | HOH1035 |
| A | HOH1038 |
| A | HOH1042 |
| A | HOH1043 |
| A | GLY11 |
| A | HOH1049 |
| A | ALA12 |
| A | VAL13 |
| A | ARG33 |
| A | TYR56 |
| A | ALA69 |
| A | VAL70 |
| site_id | AC2 |
| Number of Residues | 33 |
| Details | binding site for residue NDP B 800 |
| Chain | Residue |
| B | GLY9 |
| B | PRO10 |
| B | GLY11 |
| B | ALA12 |
| B | VAL13 |
| B | ARG33 |
| B | TYR56 |
| B | VAL70 |
| B | LYS71 |
| B | GLN74 |
| B | ALA77 |
| B | VAL78 |
| B | GLN96 |
| B | ASN97 |
| B | VAL115 |
| B | ILE117 |
| B | SER118 |
| B | GLY119 |
| B | LYS121 |
| B | GLU251 |
| B | HOH941 |
| B | HOH947 |
| B | HOH974 |
| B | HOH978 |
| B | HOH989 |
| B | HOH992 |
| B | HOH995 |
| B | HOH1001 |
| B | HOH1002 |
| B | HOH1006 |
| B | HOH1007 |
| B | HOH1021 |
| B | HOH1055 |
