Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0016020 | cellular_component | membrane |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | binding site for residue 4B2 A 401 |
Chain | Residue |
A | GLY11 |
A | GLY230 |
A | HOH656 |
A | HOH775 |
A | HOH811 |
A | HOH849 |
A | GLN12 |
A | GLY13 |
A | ASP32 |
A | TYR71 |
A | PHE108 |
A | ILE110 |
A | TRP115 |
A | ASP228 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue GOL A 402 |
Chain | Residue |
A | ASP318 |
A | HOH642 |
A | HOH739 |
A | HOH748 |
B | SER58 |
B | THR59 |
B | ARG61 |
B | ARG96 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue GOL A 403 |
Chain | Residue |
A | ARG96 |
A | ASN98 |
A | GLU134 |
A | SER139 |
A | HOH534 |
site_id | AC4 |
Number of Residues | 16 |
Details | binding site for residue 4B2 B 401 |
Chain | Residue |
B | GLY11 |
B | GLN12 |
B | GLY13 |
B | LEU30 |
B | ASP32 |
B | TYR71 |
B | PHE108 |
B | ILE110 |
B | TRP115 |
B | ILE118 |
B | ASP228 |
B | GLY230 |
B | THR232 |
B | HOH616 |
B | HOH726 |
B | HOH759 |
site_id | AC5 |
Number of Residues | 8 |
Details | binding site for residue GOL B 402 |
Chain | Residue |
A | SER58 |
A | THR59 |
A | ARG61 |
A | ARG96 |
B | ASP318 |
B | HOH508 |
B | HOH531 |
B | HOH735 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue GOL B 403 |
Chain | Residue |
B | ARG96 |
B | ASN98 |
B | GLU134 |
B | GLN143 |
B | HOH621 |
B | HOH635 |
B | HOH823 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
Chain | Residue | Details |
A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP32 | |
A | ASP228 | |
B | ASP32 | |
B | ASP228 | |
Chain | Residue | Details |
A | LYS65 | |
B | LYS218 | |
B | LYS224 | |
B | LYS238 | |
B | LYS239 | |
B | LYS246 | |
A | LYS214 | |
A | LYS218 | |
A | LYS224 | |
A | LYS238 | |
A | LYS239 | |
A | LYS246 | |
B | LYS65 | |
B | LYS214 | |
site_id | SWS_FT_FI3 |
Number of Residues | 8 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN92 | |
A | ASN111 | |
A | ASN162 | |
A | ASN293 | |
B | ASN92 | |
B | ASN111 | |
B | ASN162 | |
B | ASN293 | |