Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for Di-peptide VAL A 401 and IVA A 406 |
Chain | Residue |
A | SER13 |
B | HOH506 |
A | ASP79 |
A | GLY213 |
A | THR214 |
A | THR215 |
A | TYR218 |
B | HOH501 |
A | HOH568 |
B | HOH505 |
site_id | AC2 |
Number of Residues | 10 |
Details | binding site for Di-peptide VAL A 402 and STA A 403 |
Chain | Residue |
A | ASP32 |
A | GLY34 |
A | TYR77 |
A | GLY78 |
A | ASP79 |
A | ASP211 |
A | GLY213 |
A | THR214 |
A | TYR218 |
A | ILE298 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for Di-peptide STA A 403 and ALA A 404 |
Chain | Residue |
A | ASP32 |
A | GLY34 |
A | TYR77 |
A | GLY78 |
A | TYR187 |
A | ASP211 |
A | GLY213 |
A | THR214 |
site_id | AC4 |
Number of Residues | 8 |
Details | binding site for Di-peptide ALA A 404 and STA A 405 |
Chain | Residue |
A | GLY34 |
A | GLY76 |
A | TYR77 |
A | ARG186 |
A | TYR187 |
B | HOH502 |
B | HOH503 |
B | HOH504 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVLDTGSSDFWV |
Chain | Residue | Details |
A | VAL29-VAL40 | |
A | VAL208-LEU219 | |