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4Y9W

Aspartic Proteinase Sapp2 Secreted from Candida Parapsilosis at 0.82 A Resolution.

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for Di-peptide VAL A 401 and IVA A 406
ChainResidue
ASER13
BHOH506
AASP79
AGLY213
ATHR214
ATHR215
ATYR218
BHOH501
AHOH568
BHOH505

site_idAC2
Number of Residues10
Detailsbinding site for Di-peptide VAL A 402 and STA A 403
ChainResidue
AASP32
AGLY34
ATYR77
AGLY78
AASP79
AASP211
AGLY213
ATHR214
ATYR218
AILE298

site_idAC3
Number of Residues8
Detailsbinding site for Di-peptide STA A 403 and ALA A 404
ChainResidue
AASP32
AGLY34
ATYR77
AGLY78
ATYR187
AASP211
AGLY213
ATHR214

site_idAC4
Number of Residues8
Detailsbinding site for Di-peptide ALA A 404 and STA A 405
ChainResidue
AGLY34
AGLY76
ATYR77
AARG186
ATYR187
BHOH502
BHOH503
BHOH504

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVLDTGSSDFWV
ChainResidueDetails
AVAL29-VAL40
AVAL208-LEU219

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PDB entries from 2024-11-13

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