4Y97
Crystal Structure of human Pol alpha B-subunit in complex with C-terminal domain of catalytic subunit
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003674 | molecular_function | molecular_function |
A | 0003677 | molecular_function | DNA binding |
A | 0005515 | molecular_function | protein binding |
A | 0005634 | cellular_component | nucleus |
A | 0005654 | cellular_component | nucleoplasm |
A | 0005658 | cellular_component | alpha DNA polymerase:primase complex |
A | 0005829 | cellular_component | cytosol |
A | 0006260 | biological_process | DNA replication |
A | 0006269 | biological_process | DNA replication, synthesis of primer |
A | 0006270 | biological_process | DNA replication initiation |
A | 0006606 | biological_process | protein import into nucleus |
B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
B | 0006260 | biological_process | DNA replication |
C | 0003674 | molecular_function | molecular_function |
C | 0003677 | molecular_function | DNA binding |
C | 0005515 | molecular_function | protein binding |
C | 0005634 | cellular_component | nucleus |
C | 0005654 | cellular_component | nucleoplasm |
C | 0005658 | cellular_component | alpha DNA polymerase:primase complex |
C | 0005829 | cellular_component | cytosol |
C | 0006260 | biological_process | DNA replication |
C | 0006269 | biological_process | DNA replication, synthesis of primer |
C | 0006270 | biological_process | DNA replication initiation |
C | 0006606 | biological_process | protein import into nucleus |
D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
D | 0006260 | biological_process | DNA replication |
E | 0003674 | molecular_function | molecular_function |
E | 0003677 | molecular_function | DNA binding |
E | 0005515 | molecular_function | protein binding |
E | 0005634 | cellular_component | nucleus |
E | 0005654 | cellular_component | nucleoplasm |
E | 0005658 | cellular_component | alpha DNA polymerase:primase complex |
E | 0005829 | cellular_component | cytosol |
E | 0006260 | biological_process | DNA replication |
E | 0006269 | biological_process | DNA replication, synthesis of primer |
E | 0006270 | biological_process | DNA replication initiation |
E | 0006606 | biological_process | protein import into nucleus |
F | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
F | 0006260 | biological_process | DNA replication |
G | 0003674 | molecular_function | molecular_function |
G | 0003677 | molecular_function | DNA binding |
G | 0005515 | molecular_function | protein binding |
G | 0005634 | cellular_component | nucleus |
G | 0005654 | cellular_component | nucleoplasm |
G | 0005658 | cellular_component | alpha DNA polymerase:primase complex |
G | 0005829 | cellular_component | cytosol |
G | 0006260 | biological_process | DNA replication |
G | 0006269 | biological_process | DNA replication, synthesis of primer |
G | 0006270 | biological_process | DNA replication initiation |
G | 0006606 | biological_process | protein import into nucleus |
H | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
H | 0006260 | biological_process | DNA replication |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN B 1501 |
Chain | Residue |
B | CYS1283 |
B | CYS1286 |
B | CYS1310 |
B | CYS1315 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue ZN B 1502 |
Chain | Residue |
B | CYS1348 |
B | CYS1353 |
B | CYS1371 |
B | CYS1374 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue ZN D 1501 |
Chain | Residue |
D | CYS1286 |
D | CYS1310 |
D | CYS1315 |
D | CYS1283 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue ZN D 1502 |
Chain | Residue |
D | CYS1348 |
D | CYS1353 |
D | CYS1371 |
D | CYS1374 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue ZN F 1501 |
Chain | Residue |
F | CYS1283 |
F | CYS1286 |
F | CYS1310 |
F | CYS1315 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue ZN F 1502 |
Chain | Residue |
F | CYS1348 |
F | CYS1353 |
F | CYS1371 |
F | CYS1374 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue ZN H 1501 |
Chain | Residue |
H | CYS1283 |
H | CYS1286 |
H | CYS1310 |
H | CYS1315 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue ZN H 1502 |
Chain | Residue |
H | CYS1348 |
H | CYS1353 |
H | CYS1371 |
H | CYS1374 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 140 |
Details | ZN_FING: CysA-type => ECO:0000250|UniProtKB:P15436 |
Chain | Residue | Details |
B | CYS1283-SER1318 | |
D | CYS1283-SER1318 | |
F | CYS1283-SER1318 | |
H | CYS1283-SER1318 |
site_id | SWS_FT_FI2 |
Number of Residues | 32 |
Details | BINDING: BINDING => ECO:0000269|PubMed:26975377, ECO:0007744|PDB:5EXR |
Chain | Residue | Details |
B | CYS1283 | |
D | CYS1286 | |
D | CYS1310 | |
D | CYS1315 | |
D | CYS1348 | |
D | CYS1353 | |
D | CYS1371 | |
D | CYS1374 | |
F | CYS1283 | |
F | CYS1286 | |
F | CYS1310 | |
B | CYS1286 | |
F | CYS1315 | |
F | CYS1348 | |
F | CYS1353 | |
F | CYS1371 | |
F | CYS1374 | |
H | CYS1283 | |
H | CYS1286 | |
H | CYS1310 | |
H | CYS1315 | |
H | CYS1348 | |
B | CYS1310 | |
H | CYS1353 | |
H | CYS1371 | |
H | CYS1374 | |
B | CYS1315 | |
B | CYS1348 | |
B | CYS1353 | |
B | CYS1371 | |
B | CYS1374 | |
D | CYS1283 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER141 | |
C | SER141 | |
E | SER141 | |
G | SER141 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER147 | |
C | SER147 | |
E | SER147 | |
G | SER147 |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER152 | |
C | SER152 | |
E | SER152 | |
G | SER152 |
site_id | SWS_FT_FI6 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER154 | |
C | SER154 | |
E | SER154 | |
G | SER154 |