Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0004713 | molecular_function | protein tyrosine kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
| D | 0004672 | molecular_function | protein kinase activity |
| D | 0004713 | molecular_function | protein tyrosine kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue 746 A 701 |
| Chain | Residue |
| A | LEU408 |
| A | ALA478 |
| A | ASN479 |
| A | GLY480 |
| A | ASN526 |
| A | LEU528 |
| A | ASP539 |
| A | TYR551 |
| A | HOH862 |
| A | HOH903 |
| A | HOH961 |
| A | PHE413 |
| A | VAL416 |
| A | ALA428 |
| A | LYS430 |
| A | THR474 |
| A | GLU475 |
| A | TYR476 |
| A | MET477 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 702 |
| Chain | Residue |
| A | GLU455 |
| A | ASN530 |
| A | GLN532 |
| A | LYS536 |
| A | HOH933 |
| A | HOH966 |
| B | GLN467 |
| B | PRO469 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue BME A 703 |
| Chain | Residue |
| A | LYS430 |
| A | VAL458 |
| A | LEU460 |
| A | THR474 |
| A | SER538 |
| A | ASP539 |
| A | PHE540 |
| A | HOH968 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | binding site for residue 746 B 701 |
| Chain | Residue |
| B | LEU408 |
| B | GLY411 |
| B | PHE413 |
| B | VAL416 |
| B | ALA428 |
| B | LYS430 |
| B | THR474 |
| B | GLU475 |
| B | TYR476 |
| B | MET477 |
| B | ALA478 |
| B | GLY480 |
| B | ASN526 |
| B | LEU528 |
| B | ASP539 |
| B | VAL546 |
| B | HOH864 |
| B | HOH917 |
| B | HOH964 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 702 |
| Chain | Residue |
| A | SER438 |
| A | GLU441 |
| B | HIS609 |
| B | HOH817 |
| B | HOH927 |
| B | HOH1017 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 703 |
| Chain | Residue |
| B | GLN516 |
| B | PHE517 |
| B | LEU518 |
| B | GLY541 |
| B | HOH833 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue BME B 704 |
| Chain | Residue |
| B | LYS430 |
| B | MET449 |
| B | VAL458 |
| B | LEU460 |
| B | ASP539 |
| B | PHE540 |
| B | HOH877 |
| B | HOH982 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue PE4 B 705 |
| Chain | Residue |
| A | TYR485 |
| A | MET489 |
| A | GLN497 |
| A | ASP531 |
| B | GLN412 |
| B | VAL415 |
| B | LYS433 |
| B | HOH1026 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | binding site for residue 746 C 1001 |
| Chain | Residue |
| C | HOH1269 |
| C | LEU408 |
| C | GLY411 |
| C | PHE413 |
| C | VAL416 |
| C | ALA428 |
| C | LYS430 |
| C | THR474 |
| C | GLU475 |
| C | TYR476 |
| C | MET477 |
| C | ALA478 |
| C | GLY480 |
| C | ASN526 |
| C | LEU528 |
| C | ASP539 |
| C | VAL546 |
| C | HOH1174 |
| C | HOH1222 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 1002 |
| Chain | Residue |
| C | GLN516 |
| C | PHE517 |
| C | LEU518 |
| C | GLY541 |
| C | HOH1129 |
| C | HOH1288 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue BME C 1003 |
| Chain | Residue |
| C | LYS430 |
| C | MET449 |
| C | VAL458 |
| C | ASP539 |
| C | PHE540 |
| C | HOH1189 |
| C | HOH1290 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue PE4 C 1004 |
| Chain | Residue |
| C | GLY411 |
| C | GLN412 |
| C | LYS433 |
| C | HOH1102 |
| C | HOH1130 |
| D | TYR485 |
| D | MET489 |
| D | GLN497 |
| D | ASP531 |
| site_id | AD4 |
| Number of Residues | 20 |
| Details | binding site for residue 746 D 701 |
| Chain | Residue |
| D | LEU408 |
| D | PHE413 |
| D | VAL416 |
| D | ALA428 |
| D | LYS430 |
| D | THR474 |
| D | GLU475 |
| D | TYR476 |
| D | MET477 |
| D | ALA478 |
| D | ASN479 |
| D | GLY480 |
| D | ASN526 |
| D | LEU528 |
| D | ASP539 |
| D | VAL546 |
| D | TYR551 |
| D | HOH886 |
| D | HOH924 |
| D | HOH993 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 702 |
| Chain | Residue |
| D | LYS430 |
| D | MET449 |
| D | VAL458 |
| D | LEU460 |
| D | ASP539 |
| D | PHE540 |
| D | HOH906 |
| D | HOH939 |
| D | HOH982 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 703 |
| Chain | Residue |
| C | GLN467 |
| C | PRO469 |
| D | ASN530 |
| D | GLN532 |
| D | VAL534 |
| D | LYS536 |
| D | HOH853 |
| D | HOH976 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 704 |
| Chain | Residue |
| D | PHE517 |
| D | LEU518 |
| D | GLY541 |
| D | HOH1033 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 705 |
| Chain | Residue |
| B | SER572 |
| B | PHE574 |
| D | ALA611 |
| D | GLN612 |
| D | GLU636 |
| D | HOH854 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 23 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGTGQFGVVKyGkwrgqyd...........VAIK |
| Chain | Residue | Details |
| A | LEU408-LYS430 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FLHrDLAARNCLV |
| Chain | Residue | Details |
| A | PHE517-VAL529 | |
