Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | binding site for residue GOL A 401 |
Chain | Residue |
A | VAL272 |
A | PRO274 |
A | TYR277 |
A | ALA312 |
A | SER329 |
A | LYS330 |
A | HOH1340 |
A | HOH1581 |
site_id | AC2 |
Number of Residues | 8 |
Details | binding site for residue 47B A 402 |
Chain | Residue |
A | ASP119 |
A | ILE122 |
A | THR223 |
A | LEU224 |
A | TYR226 |
A | PHE291 |
A | HOH753 |
A | ASP15 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue 47B A 403 |
Chain | Residue |
A | GLY80 |
A | PHE194 |
A | ASP219 |
A | THR222 |
A | TYR226 |
A | ILE304 |
A | HOH529 |
A | HOH531 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue EDO A 404 |
Chain | Residue |
A | TRP197 |
A | THR198 |
A | ASP215 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
Chain | Residue | Details |
A | LEU32-VAL43 | |
A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | ASP35 | |
A | SER199 | |