Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue ZN A 501 |
| Chain | Residue |
| A | HIS216 |
| A | HIS252 |
| A | ASP253 |
| A | ASP362 |
| A | MG502 |
| A | HOH686 |
| A | HOH883 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | HOH687 |
| A | HOH688 |
| A | HOH689 |
| A | HOH690 |
| A | HOH883 |
| A | ASP253 |
| A | ZN501 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue EPK A 503 |
| Chain | Residue |
| A | TYR211 |
| A | ASN365 |
| A | VAL380 |
| A | LYS393 |
| A | TYR394 |
| A | LEU401 |
| A | ILE412 |
| A | GLN413 |
| A | PHE416 |
| A | HOH641 |
| A | HOH713 |
| A | HOH818 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHpGvnQpF |
| Chain | Residue | Details |
| A | HIS252-PHE263 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15994308","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19350606","evidenceCode":"ECO:0000269"}]} |
