4XWH

Crystal structure of the human N-acetyl-alpha-glucosaminidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001573	biological_process	ganglioside metabolic process
A	0001774	biological_process	microglial cell activation
A	0001889	biological_process	liver development
A	0001944	biological_process	vasculature development
A	0003158	biological_process	endothelium development
A	0003170	biological_process	heart valve development
A	0003183	biological_process	mitral valve morphogenesis
A	0003220	biological_process	left ventricular cardiac muscle tissue morphogenesis
A	0004561	molecular_function	alpha-N-acetylglucosaminidase activity
A	0005764	cellular_component	lysosome
A	0005773	cellular_component	vacuole
A	0006029	biological_process	proteoglycan metabolic process
A	0006801	biological_process	superoxide metabolic process
A	0006914	biological_process	autophagy
A	0006954	biological_process	inflammatory response
A	0007028	biological_process	cytoplasm organization
A	0007030	biological_process	Golgi organization
A	0007033	biological_process	vacuole organization
A	0007040	biological_process	lysosome organization
A	0007399	biological_process	nervous system development
A	0007507	biological_process	heart development
A	0007626	biological_process	locomotory behavior
A	0008340	biological_process	determination of adult lifespan
A	0009100	biological_process	glycoprotein metabolic process
A	0009611	biological_process	response to wounding
A	0010467	biological_process	gene expression
A	0014004	biological_process	microglia differentiation
A	0016485	biological_process	protein processing
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0019538	biological_process	protein metabolic process
A	0021675	biological_process	nerve development
A	0021680	biological_process	cerebellar Purkinje cell layer development
A	0022008	biological_process	neurogenesis
A	0030200	biological_process	heparan sulfate proteoglycan catabolic process
A	0030201	biological_process	heparan sulfate proteoglycan metabolic process
A	0030202	biological_process	heparin metabolic process
A	0030203	biological_process	glycosaminoglycan metabolic process
A	0030534	biological_process	adult behavior
A	0031069	biological_process	hair follicle morphogenesis
A	0032496	biological_process	response to lipopolysaccharide
A	0032963	biological_process	collagen metabolic process
A	0034142	biological_process	toll-like receptor 4 signaling pathway
A	0034285	biological_process	response to disaccharide
A	0034599	biological_process	cellular response to oxidative stress
A	0035633	biological_process	maintenance of blood-brain barrier
A	0035640	biological_process	exploration behavior
A	0035904	biological_process	aorta development
A	0035909	biological_process	aorta morphogenesis
A	0042445	biological_process	hormone metabolic process
A	0042474	biological_process	middle ear morphogenesis
A	0042982	biological_process	amyloid precursor protein metabolic process
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0043202	cellular_component	lysosomal lumen
A	0044242	biological_process	cellular lipid catabolic process
A	0045475	biological_process	locomotor rhythm
A	0046548	biological_process	retinal rod cell development
A	0048143	biological_process	astrocyte activation
A	0048708	biological_process	astrocyte differentiation
A	0055013	biological_process	cardiac muscle cell development
A	0060041	biological_process	retina development in camera-type eye
A	0060119	biological_process	inner ear receptor cell development
A	0060173	biological_process	limb development
A	0060586	biological_process	multicellular organismal-level iron ion homeostasis
A	0061744	biological_process	motor behavior
A	0070062	cellular_component	extracellular exosome
A	0071310	biological_process	obsolete cellular response to organic substance
A	0071407	biological_process	cellular response to organic cyclic compound
A	0097577	biological_process	sequestering of iron ion
A	0097696	biological_process	cell surface receptor signaling pathway via STAT
A	0099022	biological_process	vesicle tethering
A	0150076	biological_process	neuroinflammatory response
A	1904389	biological_process	rod bipolar cell differentiation
A	1904390	biological_process	cone retinal bipolar cell differentiation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.7, ECO:0007744|PDB:4XWH

Chain	Residue	Details
A	ASN261
A	ASN272
A	ASN435
A	ASN503
A	ASN526

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|Ref.7, ECO:0007744|PDB:4XWH

Chain	Residue	Details
A	ASN532

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