4XVG
Crystal structure of Alkylhydroperoxide Reductase Subunit AhpF from Escherichia coli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000302 | biological_process | response to reactive oxygen species |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0008785 | molecular_function | alkyl hydroperoxide reductase activity |
| A | 0009321 | cellular_component | alkyl hydroperoxide reductase complex |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016668 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0051287 | molecular_function | NAD binding |
| A | 0071949 | molecular_function | FAD binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 38 |
| Details | binding site for residue FAD A 700 |
| Chain | Residue |
| A | GLY219 |
| A | GLN248 |
| A | ILE249 |
| A | THR252 |
| A | ILE255 |
| A | ASN257 |
| A | GLN288 |
| A | SER289 |
| A | ALA290 |
| A | ALA321 |
| A | THR322 |
| A | GLY221 |
| A | GLY323 |
| A | ALA324 |
| A | CYS348 |
| A | ASN454 |
| A | GLY487 |
| A | ASP488 |
| A | LYS495 |
| A | GLN496 |
| A | ILE497 |
| A | ALA500 |
| A | PRO222 |
| A | HOH810 |
| A | HOH834 |
| A | HOH874 |
| A | HOH875 |
| A | HOH876 |
| A | HOH879 |
| A | HOH882 |
| A | HOH897 |
| A | HOH950 |
| A | ALA223 |
| A | TYR230 |
| A | GLY242 |
| A | GLU243 |
| A | ARG244 |
| A | GLY247 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 21 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CphCDGpl..FkgkrVaVIGGGN |
| Chain | Residue | Details |
| A | CYS345-ASN365 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | THR478 | |
| A | ASP214 | |
| A | ARG357 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842 |
| Chain | Residue | Details |
| A | LYS354 | |
| A | LYS53 |
