4XT4

Crystal structure of Rv2671 from Mycobacteirum tuberculosis in complex with dihydropteridine ring of dihydropteroic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005829	cellular_component	cytosol
A	0008703	molecular_function	5-amino-6-(5-phosphoribosylamino)uracil reductase activity
A	0009231	biological_process	riboflavin biosynthetic process
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue NAP A 301

Chain	Residue
A	GLY84
A	GLU175
A	GLY195
A	PRO196
A	THR197
A	LEU198
A	THR201
A	HOH479
A	VAL85
A	GLY86
A	THR87
A	VAL120
A	THR121
A	ARG122
A	SER123
A	VAL173

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site_id	AC2
Number of Residues	9
Details	binding site for residue 44W A 302

Chain	Residue
A	ASN44
A	PHE45
A	ILE46
A	ASP67
A	GLU91
A	GLU193
A	THR214
A	GOL303
A	HOH450

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site_id	AC3
Number of Residues	2
Details	binding site for residue GOL A 303

Chain	Residue
A	ASP67
A	44W302

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site_id	AC4
Number of Residues	10
Details	binding site for residue GOL A 304

Chain	Residue
A	ALA63
A	GLY64
A	ALA164
A	SER166
A	TYR218
A	TYR250
A	HOH401
A	HOH402
A	HOH416
A	HOH426

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