Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 901 |
| Chain | Residue |
| A | HIS297 |
| A | HIS301 |
| A | GLU320 |
| A | GLU902 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue GLU A 902 |
| Chain | Residue |
| A | GLU264 |
| A | HIS297 |
| A | GLU298 |
| A | HIS301 |
| A | LYS319 |
| A | GLU320 |
| A | TYR376 |
| A | TYR381 |
| A | ZN901 |
| A | HOH1028 |
| A | HOH1182 |
| A | HOH1465 |
| A | GLN119 |
| A | GLU121 |
| A | MET260 |
| A | ALA262 |
| A | MET263 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue GLU A 903 |
| Chain | Residue |
| A | ALA638 |
| A | ARG641 |
| A | GLU642 |
| A | ARG686 |
| A | PHE690 |
| A | ALA722 |
| A | NA909 |
| A | HOH1004 |
| A | HOH1191 |
| A | HOH1534 |
| A | HOH1548 |
| A | HOH1640 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 904 |
| Chain | Residue |
| A | ASP452 |
| A | NA906 |
| A | GOL918 |
| A | HOH1591 |
| A | HOH1783 |
| A | HOH1804 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 905 |
| Chain | Residue |
| A | SER332 |
| A | ASP333 |
| A | GLY335 |
| A | HOH1597 |
| A | HOH1691 |
| A | HOH1795 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 906 |
| Chain | Residue |
| A | ASP452 |
| A | TYR544 |
| A | NA904 |
| A | HOH1234 |
| A | HOH1703 |
| A | HOH1788 |
| A | HOH1804 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 907 |
| Chain | Residue |
| A | ILE23 |
| A | ARG140 |
| A | PHE141 |
| A | THR142 |
| A | HOH1082 |
| A | HOH1758 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 908 |
| Chain | Residue |
| A | GLU371 |
| A | HOH1017 |
| A | HOH1070 |
| A | HOH1111 |
| A | HOH1520 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 909 |
| Chain | Residue |
| A | THR645 |
| A | GLU903 |
| A | HOH1627 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 910 |
| Chain | Residue |
| A | ARG349 |
| A | ASP566 |
| A | SER570 |
| A | GOL917 |
| A | HOH1829 |
| A | HOH1872 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 911 |
| Chain | Residue |
| A | GLN19 |
| A | ILE20 |
| A | LEU138 |
| A | HOH1634 |
| A | HOH1831 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 912 |
| Chain | Residue |
| A | GLU426 |
| A | ASP432 |
| A | SER434 |
| A | HOH1265 |
| A | HOH1780 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 913 |
| Chain | Residue |
| A | HIS771 |
| A | PHE774 |
| A | HOH1271 |
| A | HOH1467 |
| A | HOH1702 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 914 |
| Chain | Residue |
| A | SER63 |
| A | VAL64 |
| A | TRP71 |
| A | TRP74 |
| A | ARG669 |
| A | VAL670 |
| A | GLU671 |
| A | GOL916 |
| A | GOL919 |
| A | HOH1142 |
| A | HOH1267 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 915 |
| Chain | Residue |
| A | LYS286 |
| A | HOH1009 |
| A | HOH1105 |
| A | HOH1874 |
| A | THR284 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 916 |
| Chain | Residue |
| A | TRP74 |
| A | GOL914 |
| A | HOH1016 |
| A | HOH1142 |
| A | HOH1589 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 917 |
| Chain | Residue |
| A | LEU532 |
| A | TRP546 |
| A | ASP566 |
| A | ALA567 |
| A | SER570 |
| A | NA910 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 918 |
| Chain | Residue |
| A | GLN164 |
| A | ASP452 |
| A | TYR454 |
| A | NA904 |
| A | HOH1022 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 919 |
| Chain | Residue |
| A | LEU61 |
| A | VAL62 |
| A | TRP74 |
| A | ARG669 |
| A | GLU671 |
| A | GOL914 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 920 |
| Chain | Residue |
| A | MET260 |
| A | TYR376 |
| A | TYR381 |
| A | GLU382 |
| A | ARG825 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue MLI A 921 |
| Chain | Residue |
| A | PHE704 |
| A | LYS738 |
| A | TRP739 |
| A | HOH1020 |
| A | HOH1586 |
| site_id | AE4 |
| Number of Residues | 8 |
| Details | binding site for residue MLI A 922 |
| Chain | Residue |
| A | ASN259 |
| A | LYS274 |
| A | PRO779 |
| A | ASN780 |
| A | ARG783 |
| A | HOH1018 |
| A | HOH1257 |
| A | HOH1295 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VIGHEYFHNW |
| Chain | Residue | Details |
| A | VAL294-TRP303 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU298 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU121 | |
| A | GLY261 | |
| A | HIS297 | |
| A | HIS301 | |
| A | GLU320 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Transition state stabilizer => ECO:0000305 |
| Chain | Residue | Details |
| A | TYR381 | |
