4XF0
cysteine dioxygenase variant - C93A at pH 8.0 with cysteine
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005506 | molecular_function | iron ion binding |
A | 0005829 | cellular_component | cytosol |
A | 0006534 | biological_process | cysteine metabolic process |
A | 0007595 | biological_process | lactation |
A | 0008198 | molecular_function | ferrous iron binding |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016151 | molecular_function | nickel cation binding |
A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
A | 0017172 | molecular_function | cysteine dioxygenase activity |
A | 0019448 | biological_process | L-cysteine catabolic process |
A | 0033762 | biological_process | response to glucagon |
A | 0042412 | biological_process | taurine biosynthetic process |
A | 0043200 | biological_process | response to amino acid |
A | 0045471 | biological_process | response to ethanol |
A | 0046439 | biological_process | L-cysteine metabolic process |
A | 0046872 | molecular_function | metal ion binding |
A | 0051213 | molecular_function | dioxygenase activity |
A | 0051384 | biological_process | response to glucocorticoid |
A | 0051591 | biological_process | response to cAMP |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue FE A 501 |
Chain | Residue |
A | HIS86 |
A | HIS88 |
A | HIS140 |
A | CYS502 |
A | CL503 |
site_id | AC2 |
Number of Residues | 13 |
Details | binding site for residue CYS A 502 |
Chain | Residue |
A | HIS88 |
A | HIS140 |
A | HIS155 |
A | TYR157 |
A | MET179 |
A | FE501 |
A | CL503 |
A | HOH773 |
A | HOH774 |
A | TYR58 |
A | ARG60 |
A | LEU75 |
A | HIS86 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue CL A 503 |
Chain | Residue |
A | HIS88 |
A | HIS140 |
A | HIS155 |
A | TYR157 |
A | FE501 |
A | CYS502 |
A | HOH745 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16611640 |
Chain | Residue | Details |
A | HIS86 | |
A | HIS88 | |
A | HIS140 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | CROSSLNK: 3'-(S-cysteinyl)-tyrosine (Cys-Tyr) => ECO:0000269|PubMed:16611640 |
Chain | Residue | Details |
A | ALA93 | |
A | TYR157 |