4XBM

X-ray crystal structure of Notch ligand Delta-like 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0007154	biological_process	cell communication
A	0007219	biological_process	Notch signaling pathway
A	0007275	biological_process	multicellular organism development
A	0016020	cellular_component	membrane
B	0005509	molecular_function	calcium ion binding
B	0007154	biological_process	cell communication
B	0007219	biological_process	Notch signaling pathway
B	0007275	biological_process	multicellular organism development
B	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CtDlensYsCtC

Chain	Residue	Details
A	CYS343-CYS354
A	CYS420-CYS431
A	CYS458-CYS469

---

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CkCrvGwqGRyC

Chain	Residue	Details
A	CYS243-CYS254
A	CYS274-CYS285
A	CYS314-CYS325
A	CYS352-CYS363
A	CYS391-CYS402
A	CYS429-CYS440
A	CYS467-CYS478
A	CYS505-CYS516

---

site_id	PS01186
Number of Residues	15
Details	EGF_2 EGF-like domain signature 2. CkCrvGWqgrycde.C

Chain	Residue	Details
A	CYS243-CYS257
A	CYS274-CYS285
A	CYS314-CYS325
A	CYS352-CYS363
A	CYS391-CYS402
A	CYS429-CYS440
A	CYS467-CYS478

---

site_id	PS01187
Number of Residues	25
Details	EGF_CA Calcium-binding EGF-like domain signature. NvDDCassp..........Canggt..CrDgvndFsC

Chain	Residue	Details
A	ASN443-CYS467

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	Domain: {"description":"DSL","evidences":[{"source":"PROSITE-ProRule","id":"PRU00377","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	Domain: {"description":"EGF-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	56
Details	Domain: {"description":"EGF-like 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	33
Details	Domain: {"description":"EGF-like 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	31
Details	Domain: {"description":"EGF-like 4; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	32
Details	Domain: {"description":"EGF-like 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---