Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4XB6

Structure of the E. coli C-P lyase core complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0015716	biological_process	organic phosphonate transport
A	0016740	molecular_function	transferase activity
A	0019634	biological_process	organic phosphonate metabolic process
A	0019700	biological_process	organic phosphonate catabolic process
A	0061693	molecular_function	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
A	0061694	cellular_component	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
A	1904176	cellular_component	carbon phosphorus lyase complex
B	0015716	biological_process	organic phosphonate transport
B	0016740	molecular_function	transferase activity
B	0019634	biological_process	organic phosphonate metabolic process
B	0019700	biological_process	organic phosphonate catabolic process
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0061693	molecular_function	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
B	0061694	cellular_component	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
B	1904176	cellular_component	carbon phosphorus lyase complex
C	0005515	molecular_function	protein binding
C	0015716	biological_process	organic phosphonate transport
C	0016740	molecular_function	transferase activity
C	0019634	biological_process	organic phosphonate metabolic process
C	0019700	biological_process	organic phosphonate catabolic process
C	0061693	molecular_function	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C	0061694	cellular_component	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
C	1904176	cellular_component	carbon phosphorus lyase complex
D	0005515	molecular_function	protein binding
D	0015716	biological_process	organic phosphonate transport
D	0016829	molecular_function	lyase activity
D	0019634	biological_process	organic phosphonate metabolic process
D	0019700	biological_process	organic phosphonate catabolic process
D	0046872	molecular_function	metal ion binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	0098848	molecular_function	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity
D	1904176	cellular_component	carbon phosphorus lyase complex
E	0005515	molecular_function	protein binding
E	0015716	biological_process	organic phosphonate transport
E	0016740	molecular_function	transferase activity
E	0019634	biological_process	organic phosphonate metabolic process
E	0019700	biological_process	organic phosphonate catabolic process
E	0061693	molecular_function	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
E	0061694	cellular_component	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
E	1904176	cellular_component	carbon phosphorus lyase complex
F	0015716	biological_process	organic phosphonate transport
F	0016740	molecular_function	transferase activity
F	0019634	biological_process	organic phosphonate metabolic process
F	0019700	biological_process	organic phosphonate catabolic process
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0061693	molecular_function	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F	0061694	cellular_component	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
F	1904176	cellular_component	carbon phosphorus lyase complex
G	0005515	molecular_function	protein binding
G	0015716	biological_process	organic phosphonate transport
G	0016740	molecular_function	transferase activity
G	0019634	biological_process	organic phosphonate metabolic process
G	0019700	biological_process	organic phosphonate catabolic process
G	0061693	molecular_function	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
G	0061694	cellular_component	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
G	1904176	cellular_component	carbon phosphorus lyase complex
H	0005515	molecular_function	protein binding
H	0015716	biological_process	organic phosphonate transport
H	0016829	molecular_function	lyase activity
H	0019634	biological_process	organic phosphonate metabolic process
H	0019700	biological_process	organic phosphonate catabolic process
H	0046872	molecular_function	metal ion binding
H	0051536	molecular_function	iron-sulfur cluster binding
H	0051539	molecular_function	4 iron, 4 sulfur cluster binding
H	0098848	molecular_function	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity
H	1904176	cellular_component	carbon phosphorus lyase complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue SO4 C 401

Chain	Residue
A	GLN85
C	ARG57
C	GLU247
C	LEU248
C	LEU249
C	HOH560
C	HOH589
C	HOH693
C	HOH735

site_id	AC2
Number of Residues	3
Details	binding site for residue ZN C 402

Chain	Residue
C	HIS328
C	HIS333
C	HOH640

site_id	AC3
Number of Residues	10
Details	binding site for residue SO4 D 301

Chain	Residue
D	TYR46
D	GLY47
D	TRP48
D	GLY49
D	THR50
D	GLY51
D	GLY208
D	ARG209
D	HOH429
D	HOH430

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN D 302

Chain	Residue
D	CYS241
D	CYS244
D	CYS266
D	CYS272

site_id	AC5
Number of Residues	8
Details	binding site for residue SO4 G 401

Chain	Residue
G	ARG57
G	GLU247
G	LEU248
G	LEU249
G	HOH568
G	HOH569
G	HOH716
G	HOH830

site_id	AC6
Number of Residues	3
Details	binding site for residue ZN G 402

Chain	Residue
G	HIS328
G	HIS333
G	HOH631

site_id	AC7
Number of Residues	10
Details	binding site for residue SO4 H 301

Chain	Residue
H	GLY47
H	TRP48
H	GLY49
H	THR50
H	GLY51
H	GLY208
H	ARG209
H	HOH421
H	HOH423
H	HOH592

site_id	AC8
Number of Residues	4
Details	binding site for residue ZN H 302

Chain	Residue
H	CYS241
H	CYS244
H	CYS266
H	CYS272

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 949

Chain	Residue	Details
D	GLY32	hydrogen radical acceptor, hydrogen radical donor
D	CYS241	metal ligand
D	CYS244	metal ligand
D	CYS266	metal ligand
D	CYS272	covalently attached, hydrogen radical donor, nucleofuge, proton acceptor, radical combinant

site_id	MCSA2
Number of Residues	5
Details	M-CSA 949

Chain	Residue	Details
H	GLY32	hydrogen radical acceptor, hydrogen radical donor
H	CYS241	metal ligand
H	CYS244	metal ligand
H	CYS266	metal ligand
H	CYS272	covalently attached, hydrogen radical donor, nucleofuge, proton acceptor, radical combinant

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)