Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 601 |
| Chain | Residue |
| A | ASP269 |
| A | ARG501 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | ASN309 |
| A | LEU310 |
| A | ASN311 |
| A | HOH736 |
| A | HOH758 |
| A | HOH799 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | THR281 |
| A | GLY282 |
| A | HOH741 |
| A | HOH748 |
| A | LEU279 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | PHE408 |
| A | GLN410 |
| A | PRO455 |
| A | ALA456 |
| A | HOH774 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | ARG341 |
| A | HOH742 |
| B | PHE445 |
| B | PRO447 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | LEU272 |
| A | GLN273 |
| A | GLY274 |
| A | THR276 |
| A | LEU325 |
| A | HOH870 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | GLN277 |
| A | LEU278 |
| B | GLU236 |
| B | HOH765 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | VAL361 |
| A | SER379 |
| A | THR380 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | THR233 |
| A | GLY235 |
| B | EDO605 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | ASP247 |
| B | EDO604 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 611 |
| Chain | Residue |
| A | TYR470 |
| A | GLN471 |
| C | HIS114 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 612 |
| Chain | Residue |
| A | GLU236 |
| A | HOH812 |
| B | GLN277 |
| B | LEU278 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 613 |
| Chain | Residue |
| A | ASP316 |
| A | THR318 |
| A | LEU494 |
| A | PHE495 |
| A | VAL515 |
| A | VAL516 |
| A | HOH703 |
| A | HOH704 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 614 |
| Chain | Residue |
| A | ARG287 |
| A | ASN311 |
| A | HOH782 |
| B | PRO245 |
| B | ILE246 |
| B | ASP247 |
| B | HOH775 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 A 615 |
| Chain | Residue |
| A | HIS358 |
| A | GLU359 |
| A | GLU382 |
| A | HOH784 |
| A | HOH874 |
| B | GLU359 |
| B | LYS449 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 601 |
| Chain | Residue |
| B | PHE408 |
| B | GLN410 |
| B | PRO455 |
| B | ALA456 |
| B | HOH741 |
| B | HOH791 |
| B | HOH889 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| B | LEU234 |
| B | VAL248 |
| B | LEU249 |
| B | VAL515 |
| B | ALA517 |
| B | THR519 |
| B | HOH856 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | LEU272 |
| B | GLN273 |
| B | GLY274 |
| B | THR276 |
| B | LEU325 |
| B | HOH837 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| A | PHE445 |
| A | PRO447 |
| A | EDO610 |
| B | ARG341 |
| B | HOH772 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| B | HOH807 |
| B | HOH810 |
| A | EDO609 |
| B | ASN309 |
| B | LEU310 |
| B | ASN311 |
| B | HOH739 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 606 |
| Chain | Residue |
| B | TYR470 |
| B | GLN471 |
| B | SER473 |
| B | HOH805 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 607 |
| Chain | Residue |
| B | THR318 |
| B | GLU319 |
| B | ASP320 |
| B | LYS372 |
| B | ASN425 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 608 |
| Chain | Residue |
| A | PRO245 |
| B | THR281 |
| B | GLY282 |
| B | LEU310 |
| B | LYS393 |
| B | HOH754 |
| B | HOH762 |
| B | HOH879 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue IMD B 609 |
| Chain | Residue |
| A | PRO243 |
| A | PRO280 |
| A | HOH806 |
| B | PRO243 |
| B | PRO280 |
| B | THR281 |
| B | HOH756 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 201 |
| Chain | Residue |
| A | PHE434 |
| A | PRO435 |
| C | GLU46 |
| C | LEU47 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue IMD C 202 |
| Chain | Residue |
| A | ASP479 |
| A | GLN531 |
| C | THR52 |
| C | SER56 |
| C | THR57 |
| C | HOH302 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 201 |
| Chain | Residue |
| D | ARG38 |
| D | GLU46 |
| D | ALA60 |
| D | SER62 |
| D | HOH328 |
