4X4T
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACCA
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000049 | molecular_function | tRNA binding |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
A | 0003723 | molecular_function | RNA binding |
A | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0008033 | biological_process | tRNA processing |
A | 0016779 | molecular_function | nucleotidyltransferase activity |
A | 0031123 | biological_process | RNA 3'-end processing |
A | 0042245 | biological_process | RNA repair |
A | 0046872 | molecular_function | metal ion binding |
A | 0106354 | biological_process | tRNA surveillance |
A | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
C | 0000049 | molecular_function | tRNA binding |
C | 0000287 | molecular_function | magnesium ion binding |
C | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
C | 0003723 | molecular_function | RNA binding |
C | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0008033 | biological_process | tRNA processing |
C | 0016779 | molecular_function | nucleotidyltransferase activity |
C | 0031123 | biological_process | RNA 3'-end processing |
C | 0042245 | biological_process | RNA repair |
C | 0046872 | molecular_function | metal ion binding |
C | 0106354 | biological_process | tRNA surveillance |
C | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
E | 0000049 | molecular_function | tRNA binding |
E | 0000287 | molecular_function | magnesium ion binding |
E | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
E | 0003723 | molecular_function | RNA binding |
E | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
E | 0005524 | molecular_function | ATP binding |
E | 0008033 | biological_process | tRNA processing |
E | 0016779 | molecular_function | nucleotidyltransferase activity |
E | 0031123 | biological_process | RNA 3'-end processing |
E | 0042245 | biological_process | RNA repair |
E | 0046872 | molecular_function | metal ion binding |
E | 0106354 | biological_process | tRNA surveillance |
E | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
F | 0000049 | molecular_function | tRNA binding |
F | 0000287 | molecular_function | magnesium ion binding |
F | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
F | 0003723 | molecular_function | RNA binding |
F | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
F | 0005524 | molecular_function | ATP binding |
F | 0008033 | biological_process | tRNA processing |
F | 0016779 | molecular_function | nucleotidyltransferase activity |
F | 0031123 | biological_process | RNA 3'-end processing |
F | 0042245 | biological_process | RNA repair |
F | 0046872 | molecular_function | metal ion binding |
F | 0106354 | biological_process | tRNA surveillance |
F | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue GOL A 501 |
Chain | Residue |
A | LYS282 |
A | SER323 |
A | PHE326 |
A | TYR328 |
A | PRO424 |
F | LYS357 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue GOL A 502 |
Chain | Residue |
A | GLU311 |
A | ARG380 |
A | LYS381 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue GOL A 503 |
Chain | Residue |
A | VAL271 |
A | THR276 |
A | VAL278 |
A | GLU386 |
A | HOH623 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue PEG E 501 |
Chain | Residue |
A | ARG361 |
A | GLU378 |
A | LYS381 |
E | ARG284 |
site_id | AC5 |
Number of Residues | 26 |
Details | binding site for Di-nucleotide A G 29 and 5BU G 30 |
Chain | Residue |
E | TYR165 |
E | ARG224 |
E | ALA228 |
E | ASN229 |
F | ALA163 |
F | TYR165 |
F | ARG224 |
F | ALA228 |
F | ASN229 |
F | ASP291 |
G | G2 |
G | C3 |
G | C4 |
G | C6 |
G | G7 |
G | G8 |
G | C9 |
G | C24 |
G | C25 |
G | G26 |
G | G28 |
G | C31 |
G | HOH102 |
G | HOH104 |
G | HOH105 |
G | HOH107 |
site_id | AC6 |
Number of Residues | 23 |
Details | binding site for Di-nucleotide 5BU G 30 and C G 31 |
Chain | Residue |
E | ALA163 |
E | TYR165 |
E | ARG224 |
E | ALA228 |
E | ASN229 |
E | ASP291 |
F | GLU96 |
F | ALA163 |
F | TYR165 |
F | ARG224 |
F | ASP291 |
G | G1 |
G | G2 |
G | G7 |
G | G8 |
G | C9 |
G | G23 |
G | G29 |
G | A29 |
G | HOH102 |
G | HOH104 |
G | HOH106 |
G | HOH107 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0000269|PubMed:14636575, ECO:0000269|PubMed:25640237, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEU, ECO:0007744|PDB:4X4O, ECO:0007744|PDB:4X4Q, ECO:0007744|PDB:4X4S |
Chain | Residue | Details |
A | SER47 | |
C | SER47 | |
E | SER47 | |
F | SER47 |
site_id | SWS_FT_FI2 |
Number of Residues | 16 |
Details | BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0000269|PubMed:14636575, ECO:0000269|PubMed:25640237, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEU, ECO:0007744|PDB:4X4Q, ECO:0007744|PDB:4X4S |
Chain | Residue | Details |
A | ARG50 | |
E | HIS133 | |
E | LYS152 | |
E | TYR161 | |
F | ARG50 | |
F | HIS133 | |
F | LYS152 | |
F | TYR161 | |
A | HIS133 | |
A | LYS152 | |
A | TYR161 | |
C | ARG50 | |
C | HIS133 | |
C | LYS152 | |
C | TYR161 | |
E | ARG50 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0007744|PDB:1UEV |
Chain | Residue | Details |
A | GLU59 | |
C | GLU59 | |
E | GLU59 | |
F | GLU59 |
site_id | SWS_FT_FI4 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEV |
Chain | Residue | Details |
A | ASP61 | |
A | ASP110 | |
C | ASP61 | |
C | ASP110 | |
E | ASP61 | |
E | ASP110 | |
F | ASP61 | |
F | ASP110 |