4X4T

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACCA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0001680	biological_process	tRNA 3'-terminal CCA addition
A	0003723	molecular_function	RNA binding
A	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
A	0005524	molecular_function	ATP binding
A	0008033	biological_process	tRNA processing
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0031123	biological_process	RNA 3'-end processing
A	0042245	biological_process	RNA repair
A	0046872	molecular_function	metal ion binding
A	0106354	biological_process	tRNA surveillance
A	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
C	0000049	molecular_function	tRNA binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0001680	biological_process	tRNA 3'-terminal CCA addition
C	0003723	molecular_function	RNA binding
C	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
C	0005524	molecular_function	ATP binding
C	0008033	biological_process	tRNA processing
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0031123	biological_process	RNA 3'-end processing
C	0042245	biological_process	RNA repair
C	0046872	molecular_function	metal ion binding
C	0106354	biological_process	tRNA surveillance
C	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
E	0000049	molecular_function	tRNA binding
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0001680	biological_process	tRNA 3'-terminal CCA addition
E	0003723	molecular_function	RNA binding
E	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
E	0005524	molecular_function	ATP binding
E	0008033	biological_process	tRNA processing
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0031123	biological_process	RNA 3'-end processing
E	0042245	biological_process	RNA repair
E	0046872	molecular_function	metal ion binding
E	0106354	biological_process	tRNA surveillance
E	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
F	0000049	molecular_function	tRNA binding
F	0000166	molecular_function	nucleotide binding
F	0000287	molecular_function	magnesium ion binding
F	0001680	biological_process	tRNA 3'-terminal CCA addition
F	0003723	molecular_function	RNA binding
F	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
F	0005524	molecular_function	ATP binding
F	0008033	biological_process	tRNA processing
F	0016740	molecular_function	transferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0031123	biological_process	RNA 3'-end processing
F	0042245	biological_process	RNA repair
F	0046872	molecular_function	metal ion binding
F	0106354	biological_process	tRNA surveillance
F	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL A 501

Chain	Residue
A	LYS282
A	SER323
A	PHE326
A	TYR328
A	PRO424
F	LYS357

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site_id	AC2
Number of Residues	3
Details	binding site for residue GOL A 502

Chain	Residue
A	GLU311
A	ARG380
A	LYS381

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 503

Chain	Residue
A	VAL271
A	THR276
A	VAL278
A	GLU386
A	HOH623

---

site_id	AC4
Number of Residues	4
Details	binding site for residue PEG E 501

Chain	Residue
A	ARG361
A	GLU378
A	LYS381
E	ARG284

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site_id	AC5
Number of Residues	26
Details	binding site for Di-nucleotide A G 29 and 5BU G 30

Chain	Residue
E	TYR165
E	ARG224
E	ALA228
E	ASN229
F	ALA163
F	TYR165
F	ARG224
F	ALA228
F	ASN229
F	ASP291
G	G2
G	C3
G	C4
G	C6
G	G7
G	G8
G	C9
G	C24
G	C25
G	G26
G	G28
G	C31
G	HOH102
G	HOH104
G	HOH105
G	HOH107

---

site_id	AC6
Number of Residues	23
Details	binding site for Di-nucleotide 5BU G 30 and C G 31

Chain	Residue
E	ALA163
E	TYR165
E	ARG224
E	ALA228
E	ASN229
E	ASP291
F	GLU96
F	ALA163
F	TYR165
F	ARG224
F	ASP291
G	G1
G	G2
G	G7
G	G8
G	C9
G	G23
G	G29
G	A29
G	HOH102
G	HOH104
G	HOH106
G	HOH107

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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