4X4O
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix and CTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008033 | biological_process | tRNA processing |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0031123 | biological_process | RNA 3'-end processing |
| A | 0042245 | biological_process | RNA repair |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106354 | biological_process | tRNA surveillance |
| A | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
| C | 0000049 | molecular_function | tRNA binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
| C | 0003723 | molecular_function | RNA binding |
| C | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008033 | biological_process | tRNA processing |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0031123 | biological_process | RNA 3'-end processing |
| C | 0042245 | biological_process | RNA repair |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0106354 | biological_process | tRNA surveillance |
| C | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue CTP A 501 |
| Chain | Residue |
| A | GLY46 |
| A | LYS152 |
| A | TYR161 |
| A | MN502 |
| A | SER47 |
| A | GLU59 |
| A | ASP61 |
| A | PHE63 |
| A | HIS97 |
| A | TYR99 |
| A | VAL112 |
| A | THR130 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MN A 502 |
| Chain | Residue |
| A | GLU59 |
| A | ASP61 |
| A | CTP501 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue MN B 101 |
| Chain | Residue |
| B | U13 |
| B | U14 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue MN B 102 |
| Chain | Residue |
| B | G1 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue CTP C 501 |
| Chain | Residue |
| C | SER47 |
| C | GLU59 |
| C | ASP61 |
| C | PHE63 |
| C | HIS97 |
| C | TYR99 |
| C | THR130 |
| C | HIS133 |
| C | LYS152 |
| C | TYR161 |
| C | MN502 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue MN C 502 |
| Chain | Residue |
| C | GLU59 |
| C | ASP61 |
| C | CTP501 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue CTP D 101 |
| Chain | Residue |
| C | ARG76 |
| C | TYR94 |
| C | PRO98 |
| D | G1 |
| D | C31 |
| D | MN104 |
| D | MN105 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue MN D 102 |
| Chain | Residue |
| D | G11 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue MN D 103 |
| Chain | Residue |
| D | U13 |
| D | U14 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MN D 104 |
| Chain | Residue |
| C | TYR94 |
| D | G1 |
| D | CTP101 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue MN D 105 |
| Chain | Residue |
| D | CTP101 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
