Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue XMP A 500 |
| Chain | Residue |
| A | ALA49 |
| A | MET361 |
| A | GLY363 |
| A | SER364 |
| A | TYR387 |
| A | GLY389 |
| A | MET390 |
| A | GLY391 |
| A | GLU417 |
| A | GLY418 |
| A | NAD501 |
| A | MET51 |
| A | HOH623 |
| A | HOH683 |
| A | HOH684 |
| A | HOH692 |
| A | HOH694 |
| A | HOH703 |
| A | GLY304 |
| A | SER305 |
| A | CYS307 |
| A | THR309 |
| A | ASP340 |
| A | GLY341 |
| A | GLY342 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | binding site for residue NAD A 501 |
| Chain | Residue |
| A | VAL25 |
| A | LEU26 |
| A | PRO27 |
| A | ALA228 |
| A | ALA229 |
| A | ASP250 |
| A | SER251 |
| A | SER252 |
| A | HIS253 |
| A | ASN279 |
| A | GLY300 |
| A | ILE301 |
| A | GLY302 |
| A | THR309 |
| A | MET390 |
| A | GLY391 |
| A | GLU417 |
| A | GLY445 |
| A | XMP500 |
| A | HOH605 |
| A | HOH610 |
| A | HOH638 |
| A | HOH701 |
| A | HOH713 |
| A | HOH772 |
| A | HOH842 |
| A | HOH843 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue K A 502 |
| Chain | Residue |
| A | GLY302 |
| A | GLY304 |
| A | CYS307 |
| A | GLU471 |
| A | SER472 |
| A | HIS473 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ASN39 |
| A | ARG221 |
| A | ASP245 |
| A | HOH705 |
| A | HOH813 |
| site_id | AC5 |
| Number of Residues | 25 |
| Details | binding site for residue XMP B 500 |
| Chain | Residue |
| B | ALA49 |
| B | MET51 |
| B | GLY304 |
| B | SER305 |
| B | ILE306 |
| B | CYS307 |
| B | THR309 |
| B | ASP340 |
| B | GLY341 |
| B | GLY342 |
| B | MET361 |
| B | GLY363 |
| B | SER364 |
| B | TYR387 |
| B | GLY389 |
| B | MET390 |
| B | GLY391 |
| B | GLU417 |
| B | GLY418 |
| B | NAD501 |
| B | HOH618 |
| B | HOH726 |
| B | HOH728 |
| B | HOH729 |
| B | HOH749 |
| site_id | AC6 |
| Number of Residues | 28 |
| Details | binding site for residue NAD B 501 |
| Chain | Residue |
| B | GLY300 |
| B | ILE301 |
| B | GLY302 |
| B | THR309 |
| B | MET390 |
| B | GLY391 |
| B | GLU417 |
| B | GLY445 |
| B | XMP500 |
| B | HOH604 |
| B | HOH619 |
| B | HOH627 |
| B | HOH748 |
| B | HOH772 |
| B | HOH826 |
| B | HOH893 |
| B | HOH894 |
| B | VAL25 |
| B | LEU26 |
| B | PRO27 |
| B | ALA228 |
| B | ALA229 |
| B | ASP250 |
| B | SER251 |
| B | SER252 |
| B | HIS253 |
| B | SER256 |
| B | ASN279 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue K B 502 |
| Chain | Residue |
| B | GLY302 |
| B | GLY304 |
| B | CYS307 |
| B | GLU471 |
| B | SER472 |
| B | HIS473 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 B 503 |
| Chain | Residue |
| B | MET3 |
| B | LEU4 |
| B | LYS8 |
| B | ALA324 |
| B | ASP325 |
| B | HOH615 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT |
| Chain | Residue | Details |
| A | VAL297-THR309 | |
