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4WZS

Crystal structure of the Mot1 N-terminal domain in complex with TBP and NC2 bound to a promoter DNA fragment

Functional Information from GO Data
ChainGOidnamespacecontents
A0001046molecular_functioncore promoter sequence-specific DNA binding
A0005634cellular_componentnucleus
A0006366biological_processtranscription by RNA polymerase II
A0016251molecular_functionRNA polymerase II general transcription initiation factor activity
A0046982molecular_functionprotein heterodimerization activity
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0005634cellular_componentnucleus
B0016251molecular_functionRNA polymerase II general transcription initiation factor activity
B0017025molecular_functionTBP-class protein binding
B0017054cellular_componentnegative cofactor 2 complex
B0046982molecular_functionprotein heterodimerization activity
B0051123biological_processRNA polymerase II preinitiation complex assembly
B0140223molecular_functiongeneral transcription initiation factor activity
C0003677molecular_functionDNA binding
C0016887molecular_functionATP hydrolysis activity
C0017025molecular_functionTBP-class protein binding
D0003677molecular_functionDNA binding
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005667cellular_componenttranscription regulator complex
D0006352biological_processDNA-templated transcription initiation
D0006367biological_processtranscription initiation at RNA polymerase II promoter
D0042802molecular_functionidentical protein binding
Functional Information from PROSITE/UniProt
site_idPS00351
Number of Residues50
DetailsTFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePKttaLIFaSGKMvitGAKsekssrmAaqryakiI
ChainResidueDetails
DTYR52-ILE101
DTYR143-LEU192

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PDB entries from 2025-06-18

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