4WYV

Crystal Structure of Human Translin in Open Conformation

Replaces:  4JHF

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0016070	biological_process	RNA metabolic process
A	0016787	molecular_function	hydrolase activity
A	0030422	biological_process	siRNA processing
A	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
A	0042802	molecular_function	identical protein binding
A	0043565	molecular_function	sequence-specific DNA binding
A	1902555	cellular_component	endoribonuclease complex
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0016070	biological_process	RNA metabolic process
B	0016787	molecular_function	hydrolase activity
B	0030422	biological_process	siRNA processing
B	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
B	0042802	molecular_function	identical protein binding
B	0043565	molecular_function	sequence-specific DNA binding
B	1902555	cellular_component	endoribonuclease complex
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0003697	molecular_function	single-stranded DNA binding
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0016070	biological_process	RNA metabolic process
C	0016787	molecular_function	hydrolase activity
C	0030422	biological_process	siRNA processing
C	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
C	0042802	molecular_function	identical protein binding
C	0043565	molecular_function	sequence-specific DNA binding
C	1902555	cellular_component	endoribonuclease complex
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0003697	molecular_function	single-stranded DNA binding
D	0003723	molecular_function	RNA binding
D	0003729	molecular_function	mRNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0016070	biological_process	RNA metabolic process
D	0016787	molecular_function	hydrolase activity
D	0030422	biological_process	siRNA processing
D	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
D	0042802	molecular_function	identical protein binding
D	0043565	molecular_function	sequence-specific DNA binding
D	1902555	cellular_component	endoribonuclease complex
E	0003676	molecular_function	nucleic acid binding
E	0003677	molecular_function	DNA binding
E	0003697	molecular_function	single-stranded DNA binding
E	0003723	molecular_function	RNA binding
E	0003729	molecular_function	mRNA binding
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0016070	biological_process	RNA metabolic process
E	0016787	molecular_function	hydrolase activity
E	0030422	biological_process	siRNA processing
E	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
E	0042802	molecular_function	identical protein binding
E	0043565	molecular_function	sequence-specific DNA binding
E	1902555	cellular_component	endoribonuclease complex
F	0003676	molecular_function	nucleic acid binding
F	0003677	molecular_function	DNA binding
F	0003697	molecular_function	single-stranded DNA binding
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0016070	biological_process	RNA metabolic process
F	0016787	molecular_function	hydrolase activity
F	0030422	biological_process	siRNA processing
F	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
F	0042802	molecular_function	identical protein binding
F	0043565	molecular_function	sequence-specific DNA binding
F	1902555	cellular_component	endoribonuclease complex
G	0003676	molecular_function	nucleic acid binding
G	0003677	molecular_function	DNA binding
G	0003697	molecular_function	single-stranded DNA binding
G	0003723	molecular_function	RNA binding
G	0003729	molecular_function	mRNA binding
G	0004518	molecular_function	nuclease activity
G	0004519	molecular_function	endonuclease activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0016070	biological_process	RNA metabolic process
G	0016787	molecular_function	hydrolase activity
G	0030422	biological_process	siRNA processing
G	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
G	0042802	molecular_function	identical protein binding
G	0043565	molecular_function	sequence-specific DNA binding
G	1902555	cellular_component	endoribonuclease complex
H	0003676	molecular_function	nucleic acid binding
H	0003677	molecular_function	DNA binding
H	0003697	molecular_function	single-stranded DNA binding
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0004518	molecular_function	nuclease activity
H	0004519	molecular_function	endonuclease activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0016070	biological_process	RNA metabolic process
H	0016787	molecular_function	hydrolase activity
H	0030422	biological_process	siRNA processing
H	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
H	0042802	molecular_function	identical protein binding
H	0043565	molecular_function	sequence-specific DNA binding
H	1902555	cellular_component	endoribonuclease complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Region: {"description":"DNA/RNA binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	168
Details	Region: {"description":"Leucine-zipper","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---