Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0022617 | biological_process | extracellular matrix disassembly |
| A | 0031012 | cellular_component | extracellular matrix |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0072562 | cellular_component | blood microparticle |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006508 | biological_process | proteolysis |
| B | 0007586 | biological_process | digestion |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0022617 | biological_process | extracellular matrix disassembly |
| B | 0031012 | cellular_component | extracellular matrix |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0072562 | cellular_component | blood microparticle |
| C | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| I | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU77 |
| A | GLU80 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 301 |
| Chain | Residue |
| B | HOH404 |
| B | HOH422 |
| B | GLU70 |
| B | ASN72 |
| B | VAL75 |
| B | GLU80 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 101 |
| Chain | Residue |
| C | ARG20 |
| C | TYR35 |
| C | ALA40 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 102 |
| Chain | Residue |
| C | ARG39 |
| C | ALA40 |
| I | PRO2 |
| I | ASP3 |
| I | PHE4 |
| I | ARG42 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 I 101 |
| Chain | Residue |
| B | ARG96 |
| I | ARG20 |
| I | TYR35 |
| I | ALA40 |
| I | HOH209 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 I 102 |
| Chain | Residue |
| C | ARG42 |
| I | GLU7 |
| I | LYS41 |
| I | ARG42 |
| I | HOH201 |
| I | HOH203 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAGHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FvyGGCrakrnnFksaedC |
| Chain | Residue | Details |
| C | PHE33-CYS51 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Reactive bond for trypsin |
| Chain | Residue | Details |
| C | LYS15 | |
| I | LYS15 | |
| A | ALA195 | |
| B | HIS57 | |
| B | ASP102 | |
| B | ALA195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| B | GLU70 | |
| B | ASN72 | |
| B | VAL75 | |
| B | GLU80 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Required for specificity => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP189 | |
| B | ASP189 | |
| Chain | Residue | Details |
| A | TYR151 | |
| B | TYR151 | |
