4WX7
Crystal structure of adenovirus 8 protease with a nitrile inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042025 | cellular_component | host cell nucleus |
| A | 0044423 | cellular_component | virion component |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0042025 | cellular_component | host cell nucleus |
| C | 0044423 | cellular_component | virion component |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 3VJ A 301 |
| Chain | Residue |
| A | GLY2 |
| A | GLY51 |
| A | GLY52 |
| A | VAL53 |
| A | HIS54 |
| A | TRP55 |
| A | GLN115 |
| A | CYS122 |
| A | SER3 |
| A | GLU5 |
| A | THR24 |
| A | HIS25 |
| A | ASP26 |
| A | ASN44 |
| A | GLY47 |
| A | ARG48 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | binding site for Di-peptide 3VJ C 301 and CYS C 122 |
| Chain | Residue |
| C | SER1 |
| C | GLY2 |
| C | SER3 |
| C | SER4 |
| C | GLU5 |
| C | GLN6 |
| C | THR24 |
| C | HIS25 |
| C | ASP26 |
| C | ASN44 |
| C | ALA46 |
| C | GLY47 |
| C | ARG48 |
| C | GLY51 |
| C | GLY52 |
| C | VAL53 |
| C | HIS54 |
| C | TRP55 |
| C | GLN115 |
| C | ALA120 |
| C | ALA121 |
| C | GLY123 |
| C | LEU124 |
| C | PHE125 |
| C | CYS126 |
