4WX4
Crystal structure of adenovirus 8 protease in complex with a nitrile inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042025 | cellular_component | host cell nucleus |
| A | 0044423 | cellular_component | virion component |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue 3VF A 301 |
| Chain | Residue |
| A | SER1 |
| A | GLY47 |
| A | ARG48 |
| A | GLY51 |
| A | GLY52 |
| A | VAL53 |
| A | TRP55 |
| A | GLN115 |
| A | SER119 |
| A | ALA120 |
| A | ALA121 |
| A | SER3 |
| A | CYS122 |
| A | EPE302 |
| A | SER4 |
| A | GLU5 |
| A | THR24 |
| A | HIS25 |
| A | ASP26 |
| A | ASN44 |
| A | ALA46 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue EPE A 302 |
| Chain | Residue |
| A | LEU22 |
| A | GLY23 |
| A | THR24 |
| A | HIS25 |
| A | ASP26 |
| A | ARG48 |
| A | 3VF301 |
| A | HOH569 |
| A | HOH599 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GLY C 401 |
| Chain | Residue |
| A | MET141 |
| A | ASP142 |
| A | MET147 |
| A | LEU150 |
| A | GLY152 |
| C | VAL301 |
| C | HOH512 |
