4WWA

Crystal structure of binary complex Bud32-Cgi121

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000282	biological_process	cellular bud site selection
A	0000408	cellular_component	EKC/KEOPS complex
A	0000722	biological_process	telomere maintenance via recombination
A	0000723	biological_process	telomere maintenance
A	0000781	cellular_component	chromosome, telomeric region
A	0002949	biological_process	tRNA threonylcarbamoyladenosine modification
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006468	biological_process	protein phosphorylation
A	0008033	biological_process	tRNA processing
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0070525	biological_process	tRNA threonylcarbamoyladenosine metabolic process
A	0106310	molecular_function	protein serine kinase activity
A	1990145	biological_process	maintenance of translational fidelity
B	0000408	cellular_component	EKC/KEOPS complex
B	0000722	biological_process	telomere maintenance via recombination
B	0000723	biological_process	telomere maintenance
B	0000781	cellular_component	chromosome, telomeric region
B	0002949	biological_process	tRNA threonylcarbamoyladenosine modification
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0005829	cellular_component	cytosol
B	0006310	biological_process	DNA recombination
B	0008033	biological_process	tRNA processing
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	1990145	biological_process	maintenance of translational fidelity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 301

Chain	Residue
A	VAL91
A	GLU107
A	LEU109
A	HIS179
B	ARG170

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site_id	AC2
Number of Residues	2
Details	binding site for residue SO4 A 302

Chain	Residue
A	THR163
A	SER165

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site_id	AC3
Number of Residues	2
Details	binding site for residue SO4 A 303

Chain	Residue
A	SER135
A	ASP136

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site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 B 201

Chain	Residue
B	ILE134
B	GLU135
B	ASN140

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site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 B 202

Chain	Residue
A	TYR100
B	GLU63
B	ASN67
B	ARG70
B	ARG143

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Functional Information from PROSITE/UniProt

site_id	PS00109
Number of Residues	13
Details	PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YCHgDLTSSNIVL

Chain	Residue	Details
A	TYR157-LEU169

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10028

Chain	Residue	Details
A	ASP161

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	ILE22
A	LYS43

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine; by autocatalysis => ECO:0000269|PubMed:12023889

Chain	Residue	Details
A	SER187
A	SER189

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