4WU3
Structure of the PTP-like myo-inositol phosphatase from Mitsuokella multacida in complex with myo-inositol-(1,3,4,5)-tetrakisphosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016158 | molecular_function | inositol hexakisphosphate 3-phosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0016158 | molecular_function | inositol hexakisphosphate 3-phosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0016158 | molecular_function | inositol hexakisphosphate 3-phosphatase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0016158 | molecular_function | inositol hexakisphosphate 3-phosphatase activity |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue 4IP A 701 |
| Chain | Residue |
| A | LYS296 |
| A | LYS297 |
| A | TYR305 |
| A | HOH804 |
| A | HOH867 |
| A | HOH890 |
| A | HOH1108 |
| A | HOH1174 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue 4IP A 702 |
| Chain | Residue |
| A | ASP449 |
| A | LYS485 |
| A | ASP519 |
| A | HIS520 |
| A | SER548 |
| A | GLN549 |
| A | ALA550 |
| A | GLY551 |
| A | ALA552 |
| A | GLY553 |
| A | ARG554 |
| A | LYS600 |
| A | TYR604 |
| A | HOH805 |
| A | HOH815 |
| A | HOH816 |
| A | HOH857 |
| A | HOH992 |
| A | HOH997 |
| A | HOH1006 |
| A | ARG351 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue PO4 A 703 |
| Chain | Residue |
| A | ASP221 |
| A | SER250 |
| A | TYR251 |
| A | ALA252 |
| A | GLY253 |
| A | MET254 |
| A | GLY255 |
| A | ARG256 |
| A | HOH811 |
| A | HOH875 |
| A | HOH953 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 704 |
| Chain | Residue |
| A | GLN310 |
| A | HIS314 |
| A | VAL338 |
| A | ASN339 |
| A | HOH820 |
| A | HOH864 |
| A | HOH891 |
| B | GLN310 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 705 |
| Chain | Residue |
| A | MET97 |
| A | ASN98 |
| A | TYR237 |
| A | PRO241 |
| A | ALA244 |
| A | LEU246 |
| A | HIS264 |
| A | LYS268 |
| A | HOH1061 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 706 |
| Chain | Residue |
| A | PHE275 |
| A | GLN313 |
| A | TYR316 |
| A | ASP317 |
| A | HOH841 |
| A | HOH1079 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue 4IP B 701 |
| Chain | Residue |
| B | LYS296 |
| B | LYS297 |
| B | TYR305 |
| B | HOH810 |
| B | HOH868 |
| B | HOH878 |
| B | HOH960 |
| B | HOH1134 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 B 702 |
| Chain | Residue |
| B | ASP519 |
| B | SER548 |
| B | GLN549 |
| B | ALA550 |
| B | GLY551 |
| B | ALA552 |
| B | GLY553 |
| B | ARG554 |
| B | HOH821 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue PO4 B 703 |
| Chain | Residue |
| B | ASP221 |
| B | SER250 |
| B | TYR251 |
| B | ALA252 |
| B | GLY253 |
| B | MET254 |
| B | GLY255 |
| B | ARG256 |
| B | HOH830 |
| B | HOH832 |
| B | HOH899 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 704 |
| Chain | Residue |
| B | HOH919 |
| A | GLN310 |
| B | GLN310 |
| B | HIS314 |
| B | VAL338 |
| B | ASN339 |
| B | HOH801 |
| B | HOH819 |
| B | HOH845 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 705 |
| Chain | Residue |
| B | MET97 |
| B | ASN98 |
| B | TYR237 |
| B | PRO241 |
| B | LYS242 |
| B | ALA244 |
| B | HIS264 |
| B | LYS268 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 706 |
| Chain | Residue |
| B | PHE275 |
| B | GLN313 |
| B | TYR316 |
| B | ASP317 |
| B | HOH853 |
| B | HOH874 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue 4IP C 701 |
| Chain | Residue |
| C | LYS296 |
| C | LYS297 |
| C | TYR305 |
| C | HOH805 |
| C | HOH815 |
| C | HOH983 |
| C | HOH1014 |
| C | HOH1148 |
| site_id | AD5 |
| Number of Residues | 20 |
| Details | binding site for residue 4IP C 702 |
| Chain | Residue |
| C | ARG351 |
| C | ASP449 |
| C | LYS485 |
| C | ASP519 |
| C | HIS520 |
| C | SER548 |
| C | GLN549 |
| C | ALA550 |
| C | GLY551 |
| C | ALA552 |
| C | GLY553 |
| C | ARG554 |
| C | LYS600 |
| C | TYR604 |
| C | HOH816 |
| C | HOH823 |
| C | HOH836 |
| C | HOH1054 |
| C | HOH1132 |
| C | HOH1169 |
| site_id | AD6 |
| Number of Residues | 11 |
| Details | binding site for residue PO4 C 703 |
| Chain | Residue |
| C | ASP221 |
| C | SER250 |
| C | TYR251 |
| C | ALA252 |
| C | GLY253 |
| C | MET254 |
| C | GLY255 |
| C | ARG256 |
| C | HOH846 |
| C | HOH847 |
| C | HOH914 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 704 |
| Chain | Residue |
| C | GLN310 |
| C | HIS314 |
| C | VAL338 |
| C | ASN339 |
| C | HOH861 |
| C | HOH897 |
| C | HOH917 |
| D | GLN310 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 705 |
| Chain | Residue |
| C | MET97 |
| C | ASN98 |
| C | TYR237 |
| C | ALA244 |
| C | LEU246 |
| C | HIS264 |
| C | LYS268 |
| C | HOH1024 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 706 |
| Chain | Residue |
| C | GLN313 |
| C | ASP317 |
| C | HOH884 |
| C | HOH915 |
| site_id | AE1 |
| Number of Residues | 10 |
| Details | binding site for residue 4IP D 701 |
| Chain | Residue |
| D | LYS296 |
| D | LYS297 |
| D | TYR305 |
| D | HOH841 |
| D | HOH862 |
| D | HOH878 |
| D | HOH881 |
| D | HOH885 |
| D | HOH1096 |
| D | HOH1106 |
| site_id | AE2 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 D 702 |
| Chain | Residue |
| D | ASP519 |
| D | SER548 |
| D | GLN549 |
| D | ALA550 |
| D | GLY551 |
| D | ALA552 |
| D | GLY553 |
| D | ARG554 |
| D | HOH826 |
| site_id | AE3 |
| Number of Residues | 11 |
| Details | binding site for residue PO4 D 703 |
| Chain | Residue |
| D | ASP221 |
| D | SER250 |
| D | TYR251 |
| D | ALA252 |
| D | GLY253 |
| D | MET254 |
| D | GLY255 |
| D | ARG256 |
| D | HOH833 |
| D | HOH896 |
| D | HOH917 |
| site_id | AE4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 704 |
| Chain | Residue |
| C | GLN310 |
| D | GLN310 |
| D | HIS314 |
| D | VAL338 |
| D | ASN339 |
| D | HOH803 |
| D | HOH856 |
| D | HOH882 |
| D | HOH903 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 705 |
| Chain | Residue |
| D | MET97 |
| D | ASN98 |
| D | TYR237 |
| D | LYS242 |
| D | ALA244 |
| D | HIS264 |
| D | LYS268 |
| D | HOH929 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 706 |
| Chain | Residue |
| D | PHE275 |
| D | GLN313 |
| D | ASP317 |
| D | HOH860 |
| D | HOH928 |
