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4WT9

APO CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH E86Q E87Q S15G C223H V321I AND DELTA8 MUTATIONS

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0003968molecular_functionRNA-dependent RNA polymerase activity
A0039694biological_processviral RNA genome replication
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue CL A 601
ChainResidue
AGLY375
AARG377
AGLY378
AARG379

site_idAC2
Number of Residues6
Detailsbinding site for residue EPE A 602
ChainResidue
AHOH864
AASN142
AVAL144
AARG394
AHIS402
AHOH796

site_idAC3
Number of Residues3
Detailsbinding site for residue PG6 A 603
ChainResidue
ALYS100
ATYR101
ATHR137

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P26663
ChainResidueDetails
AASP220
AASP318
AASP319

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PDB entries from 2024-11-06

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