4WSH
Crystal structure of Probable Uroporphyrinogen decarboxylase (UPD) (URO-D) from Pseudomonas aeruginosa
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004853 | molecular_function | uroporphyrinogen decarboxylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006778 | biological_process | porphyrin-containing compound metabolic process |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019353 | biological_process | protoporphyrinogen IX biosynthetic process from glutamate |
| B | 0004853 | molecular_function | uroporphyrinogen decarboxylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006778 | biological_process | porphyrin-containing compound metabolic process |
| B | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| B | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| B | 0006783 | biological_process | heme biosynthetic process |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0019353 | biological_process | protoporphyrinogen IX biosynthetic process from glutamate |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 400 |
| Chain | Residue |
| A | ILE276 |
| A | ASN292 |
| A | ARG311 |
| A | HOH662 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | GLY355 |
| A | HOH637 |
| A | PRO17 |
| A | VAL18 |
| A | GLY319 |
| A | THR320 |
| A | HIS354 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ARG27 |
| A | GLY30 |
| A | ARG31 |
| A | PRO332 |
| A | HOH606 |
| A | HOH663 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | ARG237 |
| A | GLU238 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | SER106 |
| A | LEU107 |
| A | ASN175 |
| A | HOH667 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | GLN16 |
| A | ARG243 |
| A | HOH703 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | ARG8 |
| A | HOH621 |
| B | ARG11 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | ARG27 |
| A | HIS328 |
| A | GLY329 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 400 |
| Chain | Residue |
| B | ILE276 |
| B | ASN292 |
| B | ARG311 |
| B | HOH532 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| B | PRO17 |
| B | VAL18 |
| B | GLY319 |
| B | THR320 |
| B | HIS354 |
| B | GLY355 |
| B | HOH604 |
| B | HOH631 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | ARG27 |
| B | GLY30 |
| B | ARG31 |
| B | PRO332 |
| B | HOH558 |
| B | HOH606 |
| B | HOH632 |
| B | HOH664 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00218 |
| Chain | Residue | Details |
| A | ARG27 | |
| B | TYR155 | |
| B | SER210 | |
| B | HIS328 | |
| A | PHE46 | |
| A | ASP78 | |
| A | TYR155 | |
| A | SER210 | |
| A | HIS328 | |
| B | ARG27 | |
| B | PHE46 | |
| B | ASP78 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00218 |
| Chain | Residue | Details |
| A | ASP78 | |
| B | ASP78 |
