4WQK

Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008871	molecular_function	aminoglycoside 2''-nucleotidyltransferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MG A 201

Chain	Residue
A	ASP44
A	ASP46
A	MG202
A	HOH483
A	HOH501
A	HOH502
A	HOH515

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 202

Chain	Residue
A	ASP86
A	MG201
A	HOH502
A	HOH558
A	ASP44
A	ASP46

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 203

Chain	Residue
A	HOH412
A	HOH421
A	HOH430
A	HOH468
A	HOH530
A	HOH540

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CL A 204

Chain	Residue
A	PHE49
A	ARG54

---

site_id	AC5
Number of Residues	3
Details	binding site for residue IPA A 205

Chain	Residue
A	GLU109
A	HOH318
A	HOH435

---

site_id	AC6
Number of Residues	1
Details	binding site for residue IPA A 206

Chain	Residue
A	PRO119

---

site_id	AC7
Number of Residues	2
Details	binding site for residue IPA A 207

Chain	Residue
A	GLU95
A	HOH416

---

site_id	AC8
Number of Residues	1
Details	binding site for residue IPA A 209

Chain	Residue
A	TYR152

---

site_id	AC9
Number of Residues	9
Details	binding site for residue GOL A 210

Chain	Residue
A	GLY27
A	GLU88
A	ILE99
A	ASN123
A	ILE128
A	ASP131
A	HOH419
A	HOH425
A	HOH448

---

site_id	AD1
Number of Residues	7
Details	binding site for residue GOL A 211

Chain	Residue
A	ASP46
A	ASP86
A	GLU88
A	ASP131
A	HOH474
A	HOH525
A	HOH561

---

site_id	AD2
Number of Residues	3
Details	binding site for residue GOL A 212

Chain	Residue
A	ARG40
A	LYS41
A	HOH560

---

site_id	AD3
Number of Residues	7
Details	binding site for residue GOL A 213

Chain	Residue
A	ALA93
A	ASP94
A	GLU95
A	GLN104
A	HOH307
A	HOH346
A	HOH556

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:25564464

Chain	Residue	Details
A	ASP86

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:25564464, ECO:0007744|PDB:4WQK, ECO:0007744|PDB:4WQL

Chain	Residue	Details
A	ASP44
A	ASP46
A	ASP86

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:25564464, ECO:0007744|PDB:4WQL

Chain	Residue	Details
A	ALA100

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