4WQK
Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, apo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008871 | molecular_function | aminoglycoside 2''-nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 201 |
| Chain | Residue |
| A | ASP44 |
| A | ASP46 |
| A | MG202 |
| A | HOH483 |
| A | HOH501 |
| A | HOH502 |
| A | HOH515 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 202 |
| Chain | Residue |
| A | ASP86 |
| A | MG201 |
| A | HOH502 |
| A | HOH558 |
| A | ASP44 |
| A | ASP46 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 203 |
| Chain | Residue |
| A | HOH412 |
| A | HOH421 |
| A | HOH430 |
| A | HOH468 |
| A | HOH530 |
| A | HOH540 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 204 |
| Chain | Residue |
| A | PHE49 |
| A | ARG54 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue IPA A 205 |
| Chain | Residue |
| A | GLU109 |
| A | HOH318 |
| A | HOH435 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue IPA A 206 |
| Chain | Residue |
| A | PRO119 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue IPA A 207 |
| Chain | Residue |
| A | GLU95 |
| A | HOH416 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue IPA A 209 |
| Chain | Residue |
| A | TYR152 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 210 |
| Chain | Residue |
| A | GLY27 |
| A | GLU88 |
| A | ILE99 |
| A | ASN123 |
| A | ILE128 |
| A | ASP131 |
| A | HOH419 |
| A | HOH425 |
| A | HOH448 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 211 |
| Chain | Residue |
| A | ASP46 |
| A | ASP86 |
| A | GLU88 |
| A | ASP131 |
| A | HOH474 |
| A | HOH525 |
| A | HOH561 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 212 |
| Chain | Residue |
| A | ARG40 |
| A | LYS41 |
| A | HOH560 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 213 |
| Chain | Residue |
| A | ALA93 |
| A | ASP94 |
| A | GLU95 |
| A | GLN104 |
| A | HOH307 |
| A | HOH346 |
| A | HOH556 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 84 |
| Details | Region: {"description":"C-terminal domain","evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28734024","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4WQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WQL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4WQL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
