4WOL
Crystal Structure of the DAP12 transmembrane domain in lipidic cubic phase
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue K A 101 |
| Chain | Residue |
| A | ASP23 |
| A | THR27 |
| B | ASP23 |
| B | THR27 |
| C | ASP23 |
| C | THR27 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue OLC B 101 |
| Chain | Residue |
| A | GLY38 |
| B | PRO13 |
| B | LEU16 |
| B | ALA17 |
| B | ASP23 |
| B | LEU29 |
| B | ARG39 |
| C | OLC101 |
| C | HOH201 |
| A | GLY22 |
| A | ASP23 |
| A | VAL34 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue OLC C 101 |
| Chain | Residue |
| A | VAL11 |
| A | LEU16 |
| A | GLY18 |
| A | LEU37 |
| B | ILE19 |
| B | ASP23 |
| B | LEU26 |
| B | OLC101 |
| C | ASP23 |
| C | HOH201 |
| C | HOH204 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue OLC C 102 |
| Chain | Residue |
| A | VAL20 |
| A | VAL25 |
| B | ALA33 |
| C | VAL25 |
| C | VAL28 |
| C | LEU29 |
| C | PHE36 |
| C | ARG39 |
| C | OLC103 |
| C | HOH211 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue OLC C 103 |
| Chain | Residue |
| B | LEU37 |
| B | GLY38 |
| B | HOH201 |
| C | GLY14 |
| C | VAL15 |
| C | GLY18 |
| C | GLY22 |
| C | LEU26 |
| C | OLC102 |
| C | HOH202 |
| C | HOH205 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 60 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"25981043","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25981043","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Site: {"description":"Important for interaction with transmembrane receptors","evidences":[{"source":"PubMed","id":"20890284","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
