4WOJ

Aspartate Semialdehyde Dehydrogenase from Francisella tularensis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004073	molecular_function	aspartate-semialdehyde dehydrogenase activity
A	0006520	biological_process	amino acid metabolic process
A	0008652	biological_process	amino acid biosynthetic process
A	0009085	biological_process	lysine biosynthetic process
A	0009086	biological_process	methionine biosynthetic process
A	0009088	biological_process	threonine biosynthetic process
A	0009089	biological_process	lysine biosynthetic process via diaminopimelate
A	0009097	biological_process	isoleucine biosynthetic process
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0019877	biological_process	diaminopimelate biosynthetic process
A	0046983	molecular_function	protein dimerization activity
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding
B	0004073	molecular_function	aspartate-semialdehyde dehydrogenase activity
B	0006520	biological_process	amino acid metabolic process
B	0008652	biological_process	amino acid biosynthetic process
B	0009085	biological_process	lysine biosynthetic process
B	0009086	biological_process	methionine biosynthetic process
B	0009088	biological_process	threonine biosynthetic process
B	0009089	biological_process	lysine biosynthetic process via diaminopimelate
B	0009097	biological_process	isoleucine biosynthetic process
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0019877	biological_process	diaminopimelate biosynthetic process
B	0046983	molecular_function	protein dimerization activity
B	0050661	molecular_function	NADP binding
B	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 A 401

Chain	Residue
A	LEU114
A	ASP117
A	GLN118
B	ASP28

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site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 402

Chain	Residue
A	ARG10
A	PRO44
A	THR45
A	LEU54

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site_id	AC3
Number of Residues	1
Details	binding site for residue SO4 B 401

Chain	Residue
B	GLU23

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site_id	AC4
Number of Residues	4
Details	binding site for residue NA B 402

Chain	Residue
A	ASP307
A	HOH503
B	VAL300
B	HOH501

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Functional Information from PROSITE/UniProt

site_id	PS01103
Number of Residues	15
Details	ASD Aspartate-semialdehyde dehydrogenase signature. VDgiCvRVpslrSHS

Chain	Residue	Details
A	VAL257-SER271

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