4WK8

FOXP3 forms a domain-swapped dimer to bridge DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006355	biological_process	regulation of DNA-templated transcription
F	0043565	molecular_function	sequence-specific DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006355	biological_process	regulation of DNA-templated transcription
G	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00658
Number of Residues	7
Details	FORK_HEAD_2 Fork head domain signature 2. WKNAIRH

Chain	Residue	Details
F	TRP381-HIS387

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Cleavage; by PCSK1 or PCSK2 => ECO:0000269|PubMed:19117830

Chain	Residue	Details
F	ARG417
G	ARG417

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q99JB6

Chain	Residue	Details
F	LYS393
G	LYS393

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