4WA8
Methanopyrus Kandleri FEN-1 nuclease
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0008409 | molecular_function | 5'-3' exonuclease activity |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0017108 | molecular_function | 5'-flap endonuclease activity |
| A | 0043137 | biological_process | DNA replication, removal of RNA primer |
| A | 0140097 | molecular_function | catalytic activity, acting on DNA |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0008409 | molecular_function | 5'-3' exonuclease activity |
| B | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| B | 0017108 | molecular_function | 5'-flap endonuclease activity |
| B | 0043137 | biological_process | DNA replication, removal of RNA primer |
| B | 0140097 | molecular_function | catalytic activity, acting on DNA |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 401 |
| Chain | Residue |
| A | TYR63 |
| A | PHE316 |
| A | SER317 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | ARG320 |
| A | HOH505 |
| A | HOH507 |
| A | HOH510 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 401 |
| Chain | Residue |
| B | HOH510 |
| B | ARG320 |
| B | HOH505 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 402 |
| Chain | Residue |
| B | TYR63 |
| B | PHE316 |
| B | SER317 |
Functional Information from PROSITE/UniProt
| site_id | PS00841 |
| Number of Residues | 15 |
| Details | XPG_1 XPG protein signature 1. IKPvYVFDGepPdLK |
| Chain | Residue | Details |
| A | ILE73-LYS87 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00614","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
