4WA8

Methanopyrus Kandleri FEN-1 nuclease

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003824	molecular_function	catalytic activity
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0006259	biological_process	DNA metabolic process
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0008409	molecular_function	5'-3' exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0017108	molecular_function	5'-flap endonuclease activity
A	0043137	biological_process	DNA replication, removal of RNA primer
A	0046872	molecular_function	metal ion binding
A	0140097	molecular_function	catalytic activity, acting on DNA
B	0000287	molecular_function	magnesium ion binding
B	0003677	molecular_function	DNA binding
B	0003824	molecular_function	catalytic activity
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004527	molecular_function	exonuclease activity
B	0006259	biological_process	DNA metabolic process
B	0006260	biological_process	DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0008409	molecular_function	5'-3' exonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0017108	molecular_function	5'-flap endonuclease activity
B	0043137	biological_process	DNA replication, removal of RNA primer
B	0046872	molecular_function	metal ion binding
B	0140097	molecular_function	catalytic activity, acting on DNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CL A 401

Chain	Residue
A	TYR63
A	PHE316
A	SER317

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site_id	AC2
Number of Residues	4
Details	binding site for residue CL A 402

Chain	Residue
A	ARG320
A	HOH505
A	HOH507
A	HOH510

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site_id	AC3
Number of Residues	3
Details	binding site for residue CL B 401

Chain	Residue
B	HOH510
B	ARG320
B	HOH505

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site_id	AC4
Number of Residues	3
Details	binding site for residue CL B 402

Chain	Residue
B	TYR63
B	PHE316
B	SER317

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Functional Information from PROSITE/UniProt

site_id	PS00841
Number of Residues	15
Details	XPG_1 XPG protein signature 1. IKPvYVFDGepPdLK

Chain	Residue	Details
A	ILE73-LYS87

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00614","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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