Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4V81

The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000166	molecular_function	nucleotide binding
a	0005515	molecular_function	protein binding
a	0005524	molecular_function	ATP binding
a	0005737	cellular_component	cytoplasm
a	0005832	cellular_component	chaperonin-containing T-complex
a	0005886	cellular_component	plasma membrane
a	0006457	biological_process	protein folding
a	0016887	molecular_function	ATP hydrolysis activity
a	0051082	molecular_function	unfolded protein binding
a	0140662	molecular_function	ATP-dependent protein folding chaperone
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005832	cellular_component	chaperonin-containing T-complex
A	0005886	cellular_component	plasma membrane
A	0006457	biological_process	protein folding
A	0016887	molecular_function	ATP hydrolysis activity
A	0051082	molecular_function	unfolded protein binding
A	0140662	molecular_function	ATP-dependent protein folding chaperone
b	0000166	molecular_function	nucleotide binding
b	0005515	molecular_function	protein binding
b	0005524	molecular_function	ATP binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005832	cellular_component	chaperonin-containing T-complex
b	0006457	biological_process	protein folding
b	0016887	molecular_function	ATP hydrolysis activity
b	0051082	molecular_function	unfolded protein binding
b	0140662	molecular_function	ATP-dependent protein folding chaperone
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005832	cellular_component	chaperonin-containing T-complex
B	0006457	biological_process	protein folding
B	0016887	molecular_function	ATP hydrolysis activity
B	0051082	molecular_function	unfolded protein binding
B	0140662	molecular_function	ATP-dependent protein folding chaperone
c	0005524	molecular_function	ATP binding
c	0006457	biological_process	protein folding
c	0016887	molecular_function	ATP hydrolysis activity
c	0051082	molecular_function	unfolded protein binding
c	0140662	molecular_function	ATP-dependent protein folding chaperone
C	0005524	molecular_function	ATP binding
C	0006457	biological_process	protein folding
C	0016887	molecular_function	ATP hydrolysis activity
C	0051082	molecular_function	unfolded protein binding
C	0140662	molecular_function	ATP-dependent protein folding chaperone
d	0000166	molecular_function	nucleotide binding
d	0005515	molecular_function	protein binding
d	0005524	molecular_function	ATP binding
d	0005737	cellular_component	cytoplasm
d	0005832	cellular_component	chaperonin-containing T-complex
d	0006457	biological_process	protein folding
d	0016887	molecular_function	ATP hydrolysis activity
d	0051082	molecular_function	unfolded protein binding
d	0140662	molecular_function	ATP-dependent protein folding chaperone
D	0000166	molecular_function	nucleotide binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005832	cellular_component	chaperonin-containing T-complex
D	0006457	biological_process	protein folding
D	0016887	molecular_function	ATP hydrolysis activity
D	0051082	molecular_function	unfolded protein binding
D	0140662	molecular_function	ATP-dependent protein folding chaperone
e	0000166	molecular_function	nucleotide binding
e	0005515	molecular_function	protein binding
e	0005524	molecular_function	ATP binding
e	0005737	cellular_component	cytoplasm
e	0005832	cellular_component	chaperonin-containing T-complex
e	0006457	biological_process	protein folding
e	0016887	molecular_function	ATP hydrolysis activity
e	0051082	molecular_function	unfolded protein binding
e	0140662	molecular_function	ATP-dependent protein folding chaperone
E	0000166	molecular_function	nucleotide binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005832	cellular_component	chaperonin-containing T-complex
E	0006457	biological_process	protein folding
E	0016887	molecular_function	ATP hydrolysis activity
E	0051082	molecular_function	unfolded protein binding
E	0140662	molecular_function	ATP-dependent protein folding chaperone
f	0000166	molecular_function	nucleotide binding
f	0005515	molecular_function	protein binding
f	0005524	molecular_function	ATP binding
f	0005737	cellular_component	cytoplasm
f	0005832	cellular_component	chaperonin-containing T-complex
f	0006457	biological_process	protein folding
f	0016887	molecular_function	ATP hydrolysis activity
f	0051082	molecular_function	unfolded protein binding
f	0140662	molecular_function	ATP-dependent protein folding chaperone
F	0000166	molecular_function	nucleotide binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005832	cellular_component	chaperonin-containing T-complex
F	0006457	biological_process	protein folding
F	0016887	molecular_function	ATP hydrolysis activity
F	0051082	molecular_function	unfolded protein binding
F	0140662	molecular_function	ATP-dependent protein folding chaperone
g	0000166	molecular_function	nucleotide binding
g	0005524	molecular_function	ATP binding
g	0005737	cellular_component	cytoplasm
g	0005832	cellular_component	chaperonin-containing T-complex
g	0006457	biological_process	protein folding
g	0016887	molecular_function	ATP hydrolysis activity
g	0051082	molecular_function	unfolded protein binding
g	0140662	molecular_function	ATP-dependent protein folding chaperone
G	0000166	molecular_function	nucleotide binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005832	cellular_component	chaperonin-containing T-complex
G	0006457	biological_process	protein folding
G	0016887	molecular_function	ATP hydrolysis activity
G	0051082	molecular_function	unfolded protein binding
G	0140662	molecular_function	ATP-dependent protein folding chaperone
h	0000166	molecular_function	nucleotide binding
h	0005515	molecular_function	protein binding
h	0005524	molecular_function	ATP binding
h	0005737	cellular_component	cytoplasm
h	0005832	cellular_component	chaperonin-containing T-complex
h	0006457	biological_process	protein folding
h	0016887	molecular_function	ATP hydrolysis activity
h	0051082	molecular_function	unfolded protein binding
h	0140662	molecular_function	ATP-dependent protein folding chaperone
H	0000166	molecular_function	nucleotide binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005832	cellular_component	chaperonin-containing T-complex
H	0006457	biological_process	protein folding
H	0016887	molecular_function	ATP hydrolysis activity
H	0051082	molecular_function	unfolded protein binding
H	0140662	molecular_function	ATP-dependent protein folding chaperone
i	0000166	molecular_function	nucleotide binding
i	0005515	molecular_function	protein binding
i	0005524	molecular_function	ATP binding
i	0005737	cellular_component	cytoplasm
i	0005832	cellular_component	chaperonin-containing T-complex
i	0005886	cellular_component	plasma membrane
i	0006457	biological_process	protein folding
i	0016887	molecular_function	ATP hydrolysis activity
i	0051082	molecular_function	unfolded protein binding
i	0140662	molecular_function	ATP-dependent protein folding chaperone
I	0000166	molecular_function	nucleotide binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005832	cellular_component	chaperonin-containing T-complex
I	0005886	cellular_component	plasma membrane
I	0006457	biological_process	protein folding
I	0016887	molecular_function	ATP hydrolysis activity
I	0051082	molecular_function	unfolded protein binding
I	0140662	molecular_function	ATP-dependent protein folding chaperone
j	0000166	molecular_function	nucleotide binding
j	0005515	molecular_function	protein binding
j	0005524	molecular_function	ATP binding
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005832	cellular_component	chaperonin-containing T-complex
j	0006457	biological_process	protein folding
j	0016887	molecular_function	ATP hydrolysis activity
j	0051082	molecular_function	unfolded protein binding
j	0140662	molecular_function	ATP-dependent protein folding chaperone
J	0000166	molecular_function	nucleotide binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005832	cellular_component	chaperonin-containing T-complex
J	0006457	biological_process	protein folding
J	0016887	molecular_function	ATP hydrolysis activity
J	0051082	molecular_function	unfolded protein binding
J	0140662	molecular_function	ATP-dependent protein folding chaperone
k	0005524	molecular_function	ATP binding
k	0006457	biological_process	protein folding
k	0016887	molecular_function	ATP hydrolysis activity
k	0051082	molecular_function	unfolded protein binding
k	0140662	molecular_function	ATP-dependent protein folding chaperone
K	0005524	molecular_function	ATP binding
K	0006457	biological_process	protein folding
K	0016887	molecular_function	ATP hydrolysis activity
K	0051082	molecular_function	unfolded protein binding
K	0140662	molecular_function	ATP-dependent protein folding chaperone
l	0000166	molecular_function	nucleotide binding
l	0005515	molecular_function	protein binding
l	0005524	molecular_function	ATP binding
l	0005737	cellular_component	cytoplasm
l	0005832	cellular_component	chaperonin-containing T-complex
l	0006457	biological_process	protein folding
l	0016887	molecular_function	ATP hydrolysis activity
l	0051082	molecular_function	unfolded protein binding
l	0140662	molecular_function	ATP-dependent protein folding chaperone
L	0000166	molecular_function	nucleotide binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005832	cellular_component	chaperonin-containing T-complex
L	0006457	biological_process	protein folding
L	0016887	molecular_function	ATP hydrolysis activity
L	0051082	molecular_function	unfolded protein binding
L	0140662	molecular_function	ATP-dependent protein folding chaperone
m	0000166	molecular_function	nucleotide binding
m	0005515	molecular_function	protein binding
m	0005524	molecular_function	ATP binding
m	0005737	cellular_component	cytoplasm
m	0005832	cellular_component	chaperonin-containing T-complex
m	0006457	biological_process	protein folding
m	0016887	molecular_function	ATP hydrolysis activity
m	0051082	molecular_function	unfolded protein binding
m	0140662	molecular_function	ATP-dependent protein folding chaperone
M	0000166	molecular_function	nucleotide binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005832	cellular_component	chaperonin-containing T-complex
M	0006457	biological_process	protein folding
M	0016887	molecular_function	ATP hydrolysis activity
M	0051082	molecular_function	unfolded protein binding
M	0140662	molecular_function	ATP-dependent protein folding chaperone
n	0000166	molecular_function	nucleotide binding
n	0005515	molecular_function	protein binding
n	0005524	molecular_function	ATP binding
n	0005737	cellular_component	cytoplasm
n	0005832	cellular_component	chaperonin-containing T-complex
n	0006457	biological_process	protein folding
n	0016887	molecular_function	ATP hydrolysis activity
n	0051082	molecular_function	unfolded protein binding
n	0140662	molecular_function	ATP-dependent protein folding chaperone
N	0000166	molecular_function	nucleotide binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005832	cellular_component	chaperonin-containing T-complex
N	0006457	biological_process	protein folding
N	0016887	molecular_function	ATP hydrolysis activity
N	0051082	molecular_function	unfolded protein binding
N	0140662	molecular_function	ATP-dependent protein folding chaperone
o	0000166	molecular_function	nucleotide binding
o	0005524	molecular_function	ATP binding
o	0005737	cellular_component	cytoplasm
o	0005832	cellular_component	chaperonin-containing T-complex
o	0006457	biological_process	protein folding
o	0016887	molecular_function	ATP hydrolysis activity
o	0051082	molecular_function	unfolded protein binding
o	0140662	molecular_function	ATP-dependent protein folding chaperone
O	0000166	molecular_function	nucleotide binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005832	cellular_component	chaperonin-containing T-complex
O	0006457	biological_process	protein folding
O	0016887	molecular_function	ATP hydrolysis activity
O	0051082	molecular_function	unfolded protein binding
O	0140662	molecular_function	ATP-dependent protein folding chaperone
p	0000166	molecular_function	nucleotide binding
p	0005515	molecular_function	protein binding
p	0005524	molecular_function	ATP binding
p	0005737	cellular_component	cytoplasm
p	0005832	cellular_component	chaperonin-containing T-complex
p	0006457	biological_process	protein folding
p	0016887	molecular_function	ATP hydrolysis activity
p	0051082	molecular_function	unfolded protein binding
p	0140662	molecular_function	ATP-dependent protein folding chaperone
P	0000166	molecular_function	nucleotide binding
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005832	cellular_component	chaperonin-containing T-complex
P	0006457	biological_process	protein folding
P	0016887	molecular_function	ATP hydrolysis activity
P	0051082	molecular_function	unfolded protein binding
P	0140662	molecular_function	ATP-dependent protein folding chaperone

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue ADP A 601

Chain	Residue
A	LEU44
A	GLY422
A	LEU462
A	LEU502
A	VAL517
A	BEF602
A	GLY45
A	PRO46
A	ASN64
A	ASP96
A	THR99
A	THR162
A	SER165
A	SER166

site_id	AC2
Number of Residues	6
Details	binding site for residue BEF A 602

Chain	Residue
A	ASP65
A	ASP96
A	GLY97
A	THR99
A	ASP404
A	ADP601

site_id	AC3
Number of Residues	15
Details	binding site for residue ADP B 601

Chain	Residue
B	THR36
B	LEU37
B	GLY38
B	ASP90
B	GLY91
B	THR93
B	SER94
B	THR159
B	THR160
B	GLY404
B	LEU444
B	LEU474
B	ILE487
B	GLU489
B	BEF602

site_id	AC4
Number of Residues	8
Details	binding site for residue BEF B 602

Chain	Residue
B	ASN58
B	ASP59
B	ASP90
B	GLY91
B	THR92
B	THR93
B	ASP386
B	ADP601

site_id	AC5
Number of Residues	14
Details	binding site for residue ADP C 1101

Chain	Residue
C	LEU39
C	GLY40
C	PRO41
C	ASP91
C	GLY92
C	THR94
C	THR95
C	ALA157
C	GLY416
C	LEU456
C	ILE484
C	ASP485
C	GLU501
C	BEF1102

site_id	AC6
Number of Residues	6
Details	binding site for residue BEF C 1102

Chain	Residue
C	ASP91
C	GLY92
C	THR93
C	THR94
C	ASP398
C	ADP1101

site_id	AC7
Number of Residues	12
Details	binding site for residue ADP D 601

Chain	Residue
D	SER38
D	LEU39
D	GLY40
D	PRO41
D	ASP91
D	GLY92
D	THR94
D	LYS161
D	LEU454
D	ARG485
D	GLN499
D	BEF602

site_id	AC8
Number of Residues	6
Details	binding site for residue BEF D 602

Chain	Residue
D	ASP91
D	GLY92
D	THR93
D	THR94
D	SER95
D	ADP601

site_id	AC9
Number of Residues	17
Details	binding site for residue ADP E 601

Chain	Residue
E	SER64
E	LEU65
E	GLY66
E	PRO67
E	ASN85
E	ASP117
E	GLY118
E	THR120
E	GLY121
E	THR186
E	LEU483
E	VAL512
E	ASP513
E	CYS514
E	VAL527
E	ASP529
E	BEF602

site_id	AD1
Number of Residues	4
Details	binding site for residue BEF E 602

Chain	Residue
E	ASP117
E	ASP425
E	ADP601
E	ASN85

site_id	AD2
Number of Residues	13
Details	binding site for residue ADP F 601

Chain	Residue
F	ASN36
F	LEU37
F	GLY38
F	PRO39
F	LYS57
F	ASP89
F	THR92
F	THR93
F	SER156
F	SER157
F	TYR419
F	ASP508
F	BEF602

site_id	AD3
Number of Residues	5
Details	binding site for residue BEF F 602

Chain	Residue
F	LYS57
F	ASP89
F	THR92
F	ASP397
F	ADP601

site_id	AD4
Number of Residues	13
Details	binding site for residue ADP G 601

Chain	Residue
G	THR43
G	GLY45
G	ASP96
G	GLY97
G	THR98
G	THR99
G	SER100
G	SER168
G	GLY413
G	LEU453
G	PHE483
G	GLU498
G	BEF602

site_id	AD5
Number of Residues	6
Details	binding site for residue BEF G 602

Chain	Residue
G	ASN64
G	ASP96
G	THR98
G	THR99
G	SER168
G	ADP601

site_id	AD6
Number of Residues	15
Details	binding site for residue ADP H 601

Chain	Residue
H	GLY47
H	PRO48
H	ASP98
H	GLY99
H	THR100
H	ASN101
H	LEU102
H	PRO165
H	SER168
H	SER169
H	ALA423
H	GLY424
H	LEU463
H	ASP506
H	BEF602

site_id	AD7
Number of Residues	6
Details	binding site for residue BEF H 602

Chain	Residue
H	ASP98
H	GLY99
H	THR100
H	ASN101
H	ASP403
H	ADP601

site_id	AD8
Number of Residues	4
Details	binding site for residue SO4 I 600

Chain	Residue
I	ASP96
I	GLY97
I	THR99
I	SER166

site_id	AD9
Number of Residues	16
Details	binding site for residue ADP J 601

Chain	Residue
J	THR36
J	LEU37
J	GLY38
J	ASN58
J	ASP90
J	GLY91
J	THR93
J	SER94
J	SER162
J	SER163
J	GLY404
J	LEU444
J	LEU474
J	ILE487
J	GLU489
J	BEF602

site_id	AE1
Number of Residues	6
Details	binding site for residue BEF J 602

Chain	Residue
J	ASN58
J	ASP59
J	ASP90
J	GLY91
J	ASP386
J	ADP601

site_id	AE2
Number of Residues	2
Details	binding site for residue SO4 K 1101

Chain	Residue
K	ASP91
K	THR94

site_id	AE3
Number of Residues	14
Details	binding site for residue ADP L 601

Chain	Residue
L	SER38
L	LEU39
L	GLY40
L	PRO41
L	GLY92
L	THR93
L	THR94
L	SER95
L	SER160
L	GLY414
L	LEU454
L	ARG485
L	GLN499
L	BEF602

site_id	AE4
Number of Residues	3
Details	binding site for residue BEF L 602

Chain	Residue
L	ASP91
L	GLY92
L	ADP601

site_id	AE5
Number of Residues	13
Details	binding site for residue ADP M 601

Chain	Residue
M	GLY66
M	PRO67
M	ASN85
M	ASP117
M	GLY118
M	THR120
M	THR186
M	ASP425
M	GLY443
M	LEU483
M	VAL512
M	ASP513
M	BEF602

site_id	AE6
Number of Residues	8
Details	binding site for residue BEF M 602

Chain	Residue
M	ASN85
M	ASP86
M	ASP117
M	GLY118
M	THR119
M	THR120
M	ASP425
M	ADP601

site_id	AE7
Number of Residues	16
Details	binding site for residue ADP N 601

Chain	Residue
N	LEU37
N	GLY38
N	PRO39
N	LYS57
N	ASP89
N	THR92
N	THR93
N	SER156
N	ALA415
N	TYR419
N	VAL491
N	ASP492
N	LEU493
N	ASN494
N	ASP508
N	BEF602

site_id	AE8
Number of Residues	6
Details	binding site for residue BEF N 602

Chain	Residue
N	LYS57
N	ASP89
N	GLY90
N	THR92
N	ASP397
N	ADP601

site_id	AE9
Number of Residues	4
Details	binding site for residue SO4 O 600

Chain	Residue
O	ASP96
O	THR98
O	THR99
O	SER100

site_id	AF1
Number of Residues	14
Details	binding site for residue ADP P 601

Chain	Residue
P	MET46
P	GLY47
P	PRO48
P	ASN66
P	ASP98
P	GLY99
P	THR100
P	ASN101
P	LEU102
P	SER169
P	ALA423
P	LEU463
P	ASP506
P	BEF602

site_id	AF2
Number of Residues	6
Details	binding site for residue BEF P 602

Chain	Residue
P	ASP98
P	GLY99
P	THR100
P	ASN101
P	ASP403
P	ADP601

site_id	AF3
Number of Residues	15
Details	binding site for residue ADP a 1601

Chain	Residue
a	LEU1044
a	GLY1045
a	PRO1046
a	ASN1064
a	ASP1096
a	GLY1097
a	THR1099
a	SER1100
a	THR1162
a	SER1165
a	SER1166
a	GLY1422
a	LEU1462
a	VAL1517
a	BEF1602

site_id	AF4
Number of Residues	7
Details	binding site for residue BEF a 1602

Chain	Residue
a	ASP1065
a	ASP1096
a	GLY1097
a	THR1098
a	THR1099
a	ASP1404
a	ADP1601

site_id	AF5
Number of Residues	16
Details	binding site for residue ADP b 1601

Chain	Residue
b	THR1036
b	LEU1037
b	GLY1038
b	ASN1058
b	ASP1090
b	GLY1091
b	THR1093
b	SER1094
b	THR1159
b	SER1162
b	GLY1404
b	LEU1444
b	LEU1474
b	ILE1487
b	GLU1489
b	BEF1602

site_id	AF6
Number of Residues	7
Details	binding site for residue BEF b 1602

Chain	Residue
b	ASP1059
b	ASP1090
b	GLY1091
b	THR1092
b	THR1093
b	ASP1386
b	ADP1601

site_id	AF7
Number of Residues	3
Details	binding site for residue SO4 c 2101

Chain	Residue
c	ASP1091
c	GLY1092
c	THR1094

site_id	AF8
Number of Residues	5
Details	binding site for residue SO4 d 1600

Chain	Residue
d	ASP1091
d	GLY1092
d	THR1093
d	THR1094
d	SER1095

site_id	AF9
Number of Residues	15
Details	binding site for residue ADP e 1601

Chain	Residue
e	GLY1066
e	PRO1067
e	ASN1085
e	ASP1117
e	GLY1118
e	THR1120
e	GLY1121
e	THR1186
e	ASP1425
e	GLY1443
e	LEU1483
e	VAL1512
e	ASP1513
e	CYS1514
e	BEF1602

site_id	AG1
Number of Residues	7
Details	binding site for residue BEF e 1602

Chain	Residue
e	ASP1086
e	ASP1117
e	GLY1118
e	THR1119
e	THR1120
e	ASP1425
e	ADP1601

site_id	AG2
Number of Residues	15
Details	binding site for residue ADP f 1601

Chain	Residue
f	ASN1036
f	LEU1037
f	GLY1038
f	PRO1039
f	LYS1057
f	ASP1089
f	THR1092
f	THR1093
f	ALA1415
f	TYR1419
f	VAL1491
f	LEU1493
f	ASN1494
f	ASP1508
f	BEF1602

site_id	AG3
Number of Residues	4
Details	binding site for residue BEF f 1602

Chain	Residue
f	LYS1057
f	ASP1089
f	ASP1397
f	ADP1601

site_id	AG4
Number of Residues	14
Details	binding site for residue ADP g 1601

Chain	Residue
g	THR1043
g	LEU1044
g	GLY1045
g	ASN1064
g	ASP1096
g	GLY1097
g	THR1098
g	THR1099
g	SER1100
g	SER1168
g	GLY1413
g	PHE1483
g	GLU1498
g	BEF1602

site_id	AG5
Number of Residues	4
Details	binding site for residue BEF g 1602

Chain	Residue
g	ASP1065
g	ASP1096
g	THR1098
g	ADP1601

site_id	AG6
Number of Residues	15
Details	binding site for residue ADP h 1601

Chain	Residue
h	MET1046
h	GLY1047
h	PRO1048
h	ASN1066
h	ASP1098
h	GLY1099
h	THR1100
h	ASN1101
h	LEU1102
h	SER1168
h	SER1169
h	ALA1423
h	LEU1463
h	HIS1494
h	BEF1602

site_id	AG7
Number of Residues	6
Details	binding site for residue BEF h 1602

Chain	Residue
h	ASP1098
h	GLY1099
h	THR1100
h	ASN1101
h	ASP1403
h	ADP1601

site_id	AG8
Number of Residues	5
Details	binding site for residue SO4 i 1600

Chain	Residue
i	LEU1044
i	ASP1096
i	GLY1097
i	THR1099
i	SER1166

site_id	AG9
Number of Residues	5
Details	binding site for residue SO4 j 1600

Chain	Residue
j	THR1036
j	ASP1090
j	GLY1091
j	THR1093
j	SER1094

site_id	AH1
Number of Residues	12
Details	binding site for residue ADP k 2101

Chain	Residue
k	LEU1039
k	GLY1040
k	ASN1059
k	ASP1091
k	THR1094
k	THR1095
k	ALA1157
k	GLY1416
k	GLY1417
k	LEU1456
k	GLU1501
k	BEF2102

site_id	AH2
Number of Residues	6
Details	binding site for residue BEF k 2102

Chain	Residue
k	ASP1091
k	GLY1092
k	THR1093
k	THR1094
k	THR1095
k	ADP2101

site_id	AH3
Number of Residues	16
Details	binding site for residue ADP l 1601

Chain	Residue
l	SER1038
l	LEU1039
l	GLY1040
l	PRO1041
l	ASP1091
l	THR1094
l	SER1160
l	LYS1161
l	GLY1413
l	GLY1414
l	GLY1415
l	ILE1450
l	LEU1454
l	ARG1485
l	GLN1499
l	BEF1602

site_id	AH4
Number of Residues	6
Details	binding site for residue BEF l 1602

Chain	Residue
l	ASP1091
l	GLY1092
l	THR1093
l	THR1094
l	SER1095
l	ADP1601

site_id	AH5
Number of Residues	15
Details	binding site for residue ADP m 1601

Chain	Residue
m	SER1064
m	GLY1066
m	PRO1067
m	ASN1085
m	ASP1117
m	GLY1118
m	THR1120
m	GLY1121
m	THR1186
m	LEU1483
m	VAL1512
m	ASP1513
m	CYS1514
m	VAL1527
m	BEF1602

site_id	AH6
Number of Residues	5
Details	binding site for residue BEF m 1602

Chain	Residue
m	ASP1086
m	ASP1117
m	GLY1118
m	ASP1425
m	ADP1601

site_id	AH7
Number of Residues	14
Details	binding site for residue ADP n 1601

Chain	Residue
n	ASN1036
n	LEU1037
n	PRO1039
n	LYS1057
n	ASP1089
n	THR1092
n	THR1093
n	SER1156
n	LEU1159
n	ALA1415
n	TYR1419
n	VAL1491
n	ILE1506
n	BEF1602

site_id	AH8
Number of Residues	4
Details	binding site for residue BEF n 1602

Chain	Residue
n	LYS1057
n	ASP1089
n	SER1157
n	ADP1601

site_id	AH9
Number of Residues	2
Details	binding site for residue SO4 o 1600

Chain	Residue
o	ASP1096
o	THR1099

site_id	AI1
Number of Residues	15
Details	binding site for residue ADP p 1601

Chain	Residue
p	GLY1047
p	PRO1048
p	ASP1098
p	GLY1099
p	THR1100
p	ASN1101
p	PRO1165
p	SER1168
p	SER1169
p	ALA1423
p	GLY1424
p	GLU1427
p	LEU1463
p	ASP1506
p	BEF1602

site_id	AI2
Number of Residues	5
Details	binding site for residue BEF p 1602

Chain	Residue
p	ASP1098
p	THR1100
p	ASN1101
p	ASP1403
p	ADP1601

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	34
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGDGTTSVTIlAgelmkeakpfleegisshLIMK

Chain	Residue	Details
o	VAL1094-LYS1127

site_id	PS00750
Number of Residues	13
Details	TCP1_1 Chaperonins TCP-1 signature 1. RTsLGPkGmdKMI

Chain	Residue	Details
l	ARG1036-ILE1048
A	LYS41-LEU53
k	ARG1036-LEU1048
n	GLU1034-LEU1046
m	LYS1062-LEU1074
p	LEU1043-ILE1055
B	LYS34-LEU46

site_id	PS00751
Number of Residues	17
Details	TCP1_2 Chaperonins TCP-1 signature 2. ISNDGATILklLdVvHP

Chain	Residue	Details
o	ILE1062-PRO1078
l	ILE1057-PRO1073
A	VAL62-PRO78
k	LEU1057-PRO1073
n	LEU1055-PRO1071
p	ILE1064-PRO1080
B	VAL56-PRO72

site_id	PS00995
Number of Residues	9
Details	TCP1_3 Chaperonins TCP-1 signature 3. QDaeVGDGT

Chain	Residue	Details
o	GLN1090-THR1098
l	GLN1085-THR1093
A	GLN90-THR98
k	GLN1085-THR1093
n	GLN1083-THR1091
m	GLN1111-THR1119
p	GLN1092-THR1100
B	GLN84-THR92

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"12872131","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)