4V7H
Structure of the 80S rRNA and proteins and P/E tRNA for eukaryotic ribosome based on cryo-EM map of Thermomyces lanuginosus ribosome at 8.9A resolution
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AB | 0003735 | molecular_function | structural constituent of ribosome |
| AB | 0005840 | cellular_component | ribosome |
| AB | 0006412 | biological_process | translation |
| AB | 0015935 | cellular_component | small ribosomal subunit |
| AC | 0003723 | molecular_function | RNA binding |
| AC | 0003735 | molecular_function | structural constituent of ribosome |
| AC | 0006412 | biological_process | translation |
| AC | 0015935 | cellular_component | small ribosomal subunit |
| AD | 0003723 | molecular_function | RNA binding |
| AD | 0003735 | molecular_function | structural constituent of ribosome |
| AD | 0006412 | biological_process | translation |
| AD | 0015935 | cellular_component | small ribosomal subunit |
| AD | 0019843 | molecular_function | rRNA binding |
| AE | 0003723 | molecular_function | RNA binding |
| AE | 0003735 | molecular_function | structural constituent of ribosome |
| AE | 0005840 | cellular_component | ribosome |
| AE | 0006412 | biological_process | translation |
| AE | 0015935 | cellular_component | small ribosomal subunit |
| AG | 0003723 | molecular_function | RNA binding |
| AG | 0003735 | molecular_function | structural constituent of ribosome |
| AG | 0006412 | biological_process | translation |
| AG | 0015935 | cellular_component | small ribosomal subunit |
| AH | 0003735 | molecular_function | structural constituent of ribosome |
| AH | 0005840 | cellular_component | ribosome |
| AH | 0006412 | biological_process | translation |
| AI | 0003735 | molecular_function | structural constituent of ribosome |
| AI | 0005840 | cellular_component | ribosome |
| AI | 0006412 | biological_process | translation |
| AJ | 0003723 | molecular_function | RNA binding |
| AJ | 0003735 | molecular_function | structural constituent of ribosome |
| AJ | 0005840 | cellular_component | ribosome |
| AJ | 0006412 | biological_process | translation |
| AJ | 0015935 | cellular_component | small ribosomal subunit |
| AK | 0003735 | molecular_function | structural constituent of ribosome |
| AK | 0005840 | cellular_component | ribosome |
| AK | 0006412 | biological_process | translation |
| AL | 0003735 | molecular_function | structural constituent of ribosome |
| AL | 0005840 | cellular_component | ribosome |
| AL | 0006412 | biological_process | translation |
| AL | 0015935 | cellular_component | small ribosomal subunit |
| AM | 0003676 | molecular_function | nucleic acid binding |
| AM | 0003723 | molecular_function | RNA binding |
| AM | 0003735 | molecular_function | structural constituent of ribosome |
| AM | 0005840 | cellular_component | ribosome |
| AM | 0006412 | biological_process | translation |
| AN | 0003735 | molecular_function | structural constituent of ribosome |
| AN | 0005840 | cellular_component | ribosome |
| AN | 0006412 | biological_process | translation |
| AN | 0008270 | molecular_function | zinc ion binding |
| AO | 0003735 | molecular_function | structural constituent of ribosome |
| AO | 0005840 | cellular_component | ribosome |
| AO | 0006412 | biological_process | translation |
| AQ | 0003735 | molecular_function | structural constituent of ribosome |
| AQ | 0005840 | cellular_component | ribosome |
| AQ | 0006412 | biological_process | translation |
| AR | 0043022 | molecular_function | ribosome binding |
| AR | 0045182 | molecular_function | translation regulator activity |
| AS | 0003735 | molecular_function | structural constituent of ribosome |
| AS | 0005840 | cellular_component | ribosome |
| AS | 0006412 | biological_process | translation |
| AT | 0003735 | molecular_function | structural constituent of ribosome |
| AT | 0005840 | cellular_component | ribosome |
| AT | 0006412 | biological_process | translation |
| B0 | 0003735 | molecular_function | structural constituent of ribosome |
| B0 | 0005840 | cellular_component | ribosome |
| B0 | 0006412 | biological_process | translation |
| B1 | 0003735 | molecular_function | structural constituent of ribosome |
| B1 | 0005840 | cellular_component | ribosome |
| B1 | 0006412 | biological_process | translation |
| B2 | 0003723 | molecular_function | RNA binding |
| B9 | 0003735 | molecular_function | structural constituent of ribosome |
| B9 | 0005840 | cellular_component | ribosome |
| B9 | 0006412 | biological_process | translation |
| BA | 0003723 | molecular_function | RNA binding |
| BA | 0003735 | molecular_function | structural constituent of ribosome |
| BA | 0006412 | biological_process | translation |
| BA | 0015934 | cellular_component | large ribosomal subunit |
| BB | 0003735 | molecular_function | structural constituent of ribosome |
| BB | 0005840 | cellular_component | ribosome |
| BB | 0006412 | biological_process | translation |
| BC | 0003735 | molecular_function | structural constituent of ribosome |
| BC | 0005840 | cellular_component | ribosome |
| BC | 0006412 | biological_process | translation |
| BD | 0003735 | molecular_function | structural constituent of ribosome |
| BD | 0005840 | cellular_component | ribosome |
| BD | 0006412 | biological_process | translation |
| BE | 0003735 | molecular_function | structural constituent of ribosome |
| BE | 0005840 | cellular_component | ribosome |
| BE | 0006412 | biological_process | translation |
| BE | 0008097 | molecular_function | 5S rRNA binding |
| BF | 0000463 | biological_process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| BF | 0003723 | molecular_function | RNA binding |
| BF | 0003735 | molecular_function | structural constituent of ribosome |
| BF | 0050825 | molecular_function | ice binding |
| BG | 0042254 | biological_process | ribosome biogenesis |
| BG | 1990904 | cellular_component | ribonucleoprotein complex |
| BH | 0003735 | molecular_function | structural constituent of ribosome |
| BH | 0005840 | cellular_component | ribosome |
| BH | 0006412 | biological_process | translation |
| BH | 0019843 | molecular_function | rRNA binding |
| BI | 0003735 | molecular_function | structural constituent of ribosome |
| BI | 0005840 | cellular_component | ribosome |
| BI | 0006412 | biological_process | translation |
| BJ | 0003735 | molecular_function | structural constituent of ribosome |
| BJ | 0005840 | cellular_component | ribosome |
| BJ | 0006412 | biological_process | translation |
| BK | 0003735 | molecular_function | structural constituent of ribosome |
| BK | 0005840 | cellular_component | ribosome |
| BK | 0006412 | biological_process | translation |
| BL | 0003735 | molecular_function | structural constituent of ribosome |
| BL | 0005840 | cellular_component | ribosome |
| BL | 0006412 | biological_process | translation |
| BM | 0003735 | molecular_function | structural constituent of ribosome |
| BM | 0005840 | cellular_component | ribosome |
| BM | 0006412 | biological_process | translation |
| BM | 0015934 | cellular_component | large ribosomal subunit |
| BM | 0050825 | molecular_function | ice binding |
| BN | 0003735 | molecular_function | structural constituent of ribosome |
| BN | 0005840 | cellular_component | ribosome |
| BN | 0006412 | biological_process | translation |
| BN | 0015934 | cellular_component | large ribosomal subunit |
| BO | 0003735 | molecular_function | structural constituent of ribosome |
| BO | 0005840 | cellular_component | ribosome |
| BO | 0006412 | biological_process | translation |
| BP | 0003723 | molecular_function | RNA binding |
| BP | 0003735 | molecular_function | structural constituent of ribosome |
| BP | 0005840 | cellular_component | ribosome |
| BP | 0006412 | biological_process | translation |
| BP | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| BP | 0050825 | molecular_function | ice binding |
| BQ | 0003735 | molecular_function | structural constituent of ribosome |
| BQ | 0005840 | cellular_component | ribosome |
| BQ | 0006412 | biological_process | translation |
| BR | 0003735 | molecular_function | structural constituent of ribosome |
| BR | 0005840 | cellular_component | ribosome |
| BR | 0006412 | biological_process | translation |
| BT | 0003735 | molecular_function | structural constituent of ribosome |
| BT | 0005840 | cellular_component | ribosome |
| BT | 0006412 | biological_process | translation |
| BT | 0019843 | molecular_function | rRNA binding |
| BU | 0003723 | molecular_function | RNA binding |
| BU | 0003735 | molecular_function | structural constituent of ribosome |
| BU | 0005840 | cellular_component | ribosome |
| BU | 0006412 | biological_process | translation |
| BU | 0015934 | cellular_component | large ribosomal subunit |
| BV | 0003735 | molecular_function | structural constituent of ribosome |
| BV | 0005840 | cellular_component | ribosome |
| BV | 0006412 | biological_process | translation |
| BW | 0003735 | molecular_function | structural constituent of ribosome |
| BW | 0005840 | cellular_component | ribosome |
| BW | 0006412 | biological_process | translation |
| BX | 0000463 | biological_process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| BX | 0003735 | molecular_function | structural constituent of ribosome |
| BX | 0005840 | cellular_component | ribosome |
| BX | 0006412 | biological_process | translation |
| BX | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| BY | 0003735 | molecular_function | structural constituent of ribosome |
| BY | 0005840 | cellular_component | ribosome |
| BY | 0006412 | biological_process | translation |
| BZ | 0003735 | molecular_function | structural constituent of ribosome |
| BZ | 0005840 | cellular_component | ribosome |
| BZ | 0006412 | biological_process | translation |
Functional Information from PROSITE/UniProt
| site_id | PS00049 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L14 Ribosomal protein L14 signature. AIVVrqakswrrr.DGvflyFedNagVI |
| Chain | Residue | Details |
| BR | ALA76-ILE102 |
| site_id | PS00050 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLTadydaldI |
| Chain | Residue | Details |
| BT | LYS120-ILE135 |
| site_id | PS00051 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L39E Ribosomal protein L39e signature. RTnntIryNakrRNWRR |
| Chain | Residue | Details |
| B1 | ARG30-ARG46 |
| site_id | PS00052 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIIkhT |
| Chain | Residue | Details |
| AG | GLU91-THR117 |
| site_id | PS00053 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAR |
| Chain | Residue | Details |
| AH | GLY100-ARG117 |
| site_id | PS00054 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD |
| Chain | Residue | Details |
| AK | LEU102-ASP124 |
| site_id | PS00055 |
| Number of Residues | 8 |
| Details | RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR |
| Chain | Residue | Details |
| AL | LYS62-ARG69 |
| site_id | PS00056 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS |
| Chain | Residue | Details |
| AQ | GLY120-SER132 |
| site_id | PS00358 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLSGQtpVqSkARyT |
| Chain | Residue | Details |
| BJ | LEU37-THR53 |
| site_id | PS00359 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L11 Ribosomal protein L11 signature. KeIlGTaqSVGcRV.D |
| Chain | Residue | Details |
| BK | LYS130-ASP144 |
| site_id | PS00360 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL |
| Chain | Residue | Details |
| AI | GLY71-LEU89 |
| site_id | PS00361 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_S10 Ribosomal protein S10 signature. AeqhNLvkkGPVrLPT |
| Chain | Residue | Details |
| AJ | ALA45-THR60 |
| site_id | PS00362 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY |
| Chain | Residue | Details |
| AO | VAL98-TYR128 |
| site_id | PS00464 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinkyesspSHIELvV |
| Chain | Residue | Details |
| BN | ARG126-VAL150 |
| site_id | PS00467 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L2 Ribosomal protein L2 signature. PktRGVAmNPvD |
| Chain | Residue | Details |
| BB | PRO197-ASP208 |
| site_id | PS00474 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L3 Ribosomal protein L3 signature. FeqnemiDaiAvTkGHGfeGvthR |
| Chain | Residue | Details |
| BC | PHE209-ARG232 |
| site_id | PS00475 |
| Number of Residues | 32 |
| Details | RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGkGrIpnvp.ViVkarfVSklAeekIraaG |
| Chain | Residue | Details |
| BV | LYS110-GLY141 |
| site_id | PS00526 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaAsvvgVGkrkVWLDP |
| Chain | Residue | Details |
| BP | GLN7-PRO26 |
| site_id | PS00527 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsshtglvrkyd.LNICRqCFR |
| Chain | Residue | Details |
| AN | ARG22-ARG44 |
| site_id | PS00548 |
| Number of Residues | 37 |
| Details | RIBOSOMAL_S3 Ribosomal protein S3 signature. AKamkfadGfLihSgqpVndfIDtatrhvlMrqGvlG |
| Chain | Residue | Details |
| AC | ALA147-GLY183 |
| site_id | PS00579 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L29 Ribosomal protein L29 signature. SLPKIKtVRKSIACV |
| Chain | Residue | Details |
| BX | SER40-VAL54 |
| site_id | PS00580 |
| Number of Residues | 21 |
| Details | RIBOSOMAL_L32E Ribosomal protein L32e signature. FkRhhsdRyhRVaen..WRKqkG |
| Chain | Residue | Details |
| B0 | PHE17-GLY37 |
| site_id | PS00585 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAvvVVGDsn.GhVGlGiktak.EVag.AI |
| Chain | Residue | Details |
| AE | GLY93-ILE125 |
| site_id | PS00628 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_S19E Ribosomal protein S19e signature. PykhidaSgsInRkVLQaLE |
| Chain | Residue | Details |
| AT | PRO90-GLU109 |
| site_id | PS00632 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI |
| Chain | Residue | Details |
| AD | LEU105-ILE129 |
| site_id | PS00634 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLtRinSgTfvkvtkatleLLklIepYV |
| Chain | Residue | Details |
| BF | VAL102-VAL134 |
| site_id | PS00646 |
| Number of Residues | 14 |
| Details | RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHfwGlrVRGQ |
| Chain | Residue | Details |
| AM | ARG123-GLN136 |
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSAswDkTLRLWDV |
| Chain | Residue | Details |
| AR | ALA80-VAL94 | |
| AR | ILE169-LEU183 | |
| AR | ILE211-LEU225 |
| site_id | PS00700 |
| Number of Residues | 22 |
| Details | RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QicrVrnKdiRkFlDGIYVshK |
| Chain | Residue | Details |
| BH | GLN163-LYS184 |
| site_id | PS00709 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkytlGyKstVKslRqGksKlIII |
| Chain | Residue | Details |
| B2 | SER20-ILE44 |
| site_id | PS00783 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L13 Ribosomal protein L13 signature. LRGMVShktarGKaalerLkVFeG |
| Chain | Residue | Details |
| BM | LEU84-GLY107 |
| site_id | PS00939 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L1E Ribosomal protein L1e signature. NhneKryATaSAIaATAvaslvlaRGH |
| Chain | Residue | Details |
| BD | ASN114-HIS140 |
| site_id | PS00962 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. AqLLLAANTHLG |
| Chain | Residue | Details |
| AB | ALA14-GLY25 |
| site_id | PS00963 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlVIVtDprsDaqaIkEasyvNIP |
| Chain | Residue | Details |
| AB | PRO118-PRO142 |
| site_id | PS00993 |
| Number of Residues | 21 |
| Details | RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTavGKlfrvgvVsIlEaG |
| Chain | Residue | Details |
| B2 | GLU76-GLY96 |
| site_id | PS01073 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGakIyPGrGtlFvRgD |
| Chain | Residue | Details |
| BS | PHE8-ASP25 |
| site_id | PS01077 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L37E Ribosomal protein L37e signature. GTpSfGkRhnks.HtlCnRCG |
| Chain | Residue | Details |
| BY | GLY4-GLY23 |
| site_id | PS01082 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CkkmgVPYaiVkGKarLG |
| Chain | Residue | Details |
| BG | CYS170-GLY187 |
| site_id | PS01106 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L18E Ribosomal protein L18e signature. KaLflSKinRPpVSVsRI |
| Chain | Residue | Details |
| BO | LYS50-ILE67 |
| site_id | PS01108 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVlVVrGskKGqe.GkI |
| Chain | Residue | Details |
| BU | ASP53-ILE70 |
| site_id | PS01144 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L31E Ribosomal protein L31e signature. VRLApeLNqAiWkRG |
| Chain | Residue | Details |
| BW | VAL49-GLY63 |
| site_id | PS01171 |
| Number of Residues | 26 |
| Details | RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikangsiqk.GmpHkfYqGkTG |
| Chain | Residue | Details |
| BQ | GLY37-GLY62 |
| site_id | PS01172 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKvvLRleC |
| Chain | Residue | Details |
| BZ | LYS63-CYS74 |
| site_id | PS01194 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGFVIYRvRVrRG |
| Chain | Residue | Details |
| BL | ASP46-GLY69 |
| site_id | PS01199 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L1 Ribosomal protein L1 signature. IkqVprlLGpqLSKAGkFPT |
| Chain | Residue | Details |
| BA | ILE117-THR136 |
| site_id | PS01257 |
| Number of Residues | 22 |
| Details | RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqqGMRgAWGKPhGlaARV |
| Chain | Residue | Details |
| BI | ALA108-VAL129 |
