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4V58

Crystal structure of fatty acid synthase from thermomyces lanuginosus at 3.1 angstrom resolution.

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0004312molecular_functionfatty acid synthase activity
A0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
A0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
A0005835cellular_componentfatty acid synthase complex
A0006633biological_processfatty acid biosynthetic process
A0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
A0016746molecular_functionacyltransferase activity
A0042759biological_processlong-chain fatty acid biosynthetic process
B0000287molecular_functionmagnesium ion binding
B0004312molecular_functionfatty acid synthase activity
B0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
B0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
B0005835cellular_componentfatty acid synthase complex
B0006633biological_processfatty acid biosynthetic process
B0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
B0016746molecular_functionacyltransferase activity
B0042759biological_processlong-chain fatty acid biosynthetic process
C0000287molecular_functionmagnesium ion binding
C0004312molecular_functionfatty acid synthase activity
C0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
C0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
C0005835cellular_componentfatty acid synthase complex
C0006633biological_processfatty acid biosynthetic process
C0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
C0016746molecular_functionacyltransferase activity
C0042759biological_processlong-chain fatty acid biosynthetic process
D0000287molecular_functionmagnesium ion binding
D0004312molecular_functionfatty acid synthase activity
D0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
D0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
D0005835cellular_componentfatty acid synthase complex
D0006633biological_processfatty acid biosynthetic process
D0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
D0016746molecular_functionacyltransferase activity
D0042759biological_processlong-chain fatty acid biosynthetic process
E0000287molecular_functionmagnesium ion binding
E0004312molecular_functionfatty acid synthase activity
E0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
E0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
E0005835cellular_componentfatty acid synthase complex
E0006633biological_processfatty acid biosynthetic process
E0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
E0016746molecular_functionacyltransferase activity
E0042759biological_processlong-chain fatty acid biosynthetic process
F0000287molecular_functionmagnesium ion binding
F0004312molecular_functionfatty acid synthase activity
F0004315molecular_function3-oxoacyl-[acyl-carrier-protein] synthase activity
F0004316molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
F0005835cellular_componentfatty acid synthase complex
F0006633biological_processfatty acid biosynthetic process
F0008897molecular_functionholo-[acyl-carrier-protein] synthase activity
F0016746molecular_functionacyltransferase activity
F0042759biological_processlong-chain fatty acid biosynthetic process
G0004312molecular_functionfatty acid synthase activity
G0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
G0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
G0004317molecular_function(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
G0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
G0005835cellular_componentfatty acid synthase complex
G0006633biological_processfatty acid biosynthetic process
G0016740molecular_functiontransferase activity
H0004312molecular_functionfatty acid synthase activity
H0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
H0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
H0004317molecular_function(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
H0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
H0005835cellular_componentfatty acid synthase complex
H0006633biological_processfatty acid biosynthetic process
H0016740molecular_functiontransferase activity
I0004312molecular_functionfatty acid synthase activity
I0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
I0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
I0004317molecular_function(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
I0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
I0005835cellular_componentfatty acid synthase complex
I0006633biological_processfatty acid biosynthetic process
I0016740molecular_functiontransferase activity
J0004312molecular_functionfatty acid synthase activity
J0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
J0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
J0004317molecular_function(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
J0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
J0005835cellular_componentfatty acid synthase complex
J0006633biological_processfatty acid biosynthetic process
J0016740molecular_functiontransferase activity
K0004312molecular_functionfatty acid synthase activity
K0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
K0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
K0004317molecular_function(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
K0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
K0005835cellular_componentfatty acid synthase complex
K0006633biological_processfatty acid biosynthetic process
K0016740molecular_functiontransferase activity
L0004312molecular_functionfatty acid synthase activity
L0004313molecular_function[acyl-carrier-protein] S-acetyltransferase activity
L0004314molecular_function[acyl-carrier-protein] S-malonyltransferase activity
L0004317molecular_function(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
L0004318molecular_functionenoyl-[acyl-carrier-protein] reductase (NADH) activity
L0005835cellular_componentfatty acid synthase complex
L0006633biological_processfatty acid biosynthetic process
L0016740molecular_functiontransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues17
Detailsbinding site for residue FMN G 2101
ChainResidue
GGLY607
GGLY748
GGLY749
GSER780
GGLY781
GGLY813
GSER814
GLEU1067
GALA1072
GMET608
GTHR609
GPRO610
GASN661
GGLY693
GLYS717
GTHR744
GARG747

site_idAC2
Number of Residues17
Detailsbinding site for residue FMN H 2101
ChainResidue
HGLY607
HMET608
HTHR609
HPRO610
HASN661
HGLY693
HLYS717
HTHR744
HARG747
HGLY748
HGLY749
HSER780
HGLY781
HGLY813
HSER814
HLEU1067
HALA1072

site_idAC3
Number of Residues17
Detailsbinding site for residue FMN I 2101
ChainResidue
IGLY607
IMET608
ITHR609
IPRO610
IASN661
IGLY693
ILYS717
ITHR744
IARG747
IGLY748
IGLY749
ISER780
IGLY781
IGLY813
ISER814
ILEU1067
IALA1072

site_idAC4
Number of Residues17
Detailsbinding site for residue FMN J 2101
ChainResidue
JGLY607
JMET608
JTHR609
JPRO610
JASN661
JGLY693
JLYS717
JTHR744
JARG747
JGLY748
JGLY749
JSER780
JGLY781
JGLY813
JSER814
JLEU1067
JALA1072

site_idAC5
Number of Residues17
Detailsbinding site for residue FMN K 2101
ChainResidue
KGLY607
KMET608
KTHR609
KPRO610
KASN661
KGLY693
KLYS717
KTHR744
KARG747
KGLY748
KGLY749
KSER780
KGLY781
KGLY813
KSER814
KLEU1067
KALA1072

site_idAC6
Number of Residues17
Detailsbinding site for residue FMN L 2101
ChainResidue
LSER814
LLEU1067
LALA1072
LGLY607
LMET608
LTHR609
LPRO610
LASN661
LGLY693
LLYS717
LTHR744
LARG747
LGLY748
LGLY749
LSER780
LGLY781
LGLY813

Functional Information from PROSITE/UniProt
site_idPS00606
Number of Residues17
DetailsKS3_1 Ketosynthase family 3 (KS3) active site signature. GPIktPVgACATAveSL
ChainResidueDetails
AGLY1271-LEU1287

site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. LVGGKSTLQNEILGDL
ChainResidueDetails
ALEU175-LEU190

218853

PDB entries from 2024-04-24

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