Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4V3P

The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
LA	0003723	molecular_function	RNA binding
LA	0003735	molecular_function	structural constituent of ribosome
LA	0005840	cellular_component	ribosome
LA	0006412	biological_process	translation
LA	0015934	cellular_component	large ribosomal subunit
LA	0022625	cellular_component	cytosolic large ribosomal subunit
LA	1990904	cellular_component	ribonucleoprotein complex
LB	0003723	molecular_function	RNA binding
LB	0003735	molecular_function	structural constituent of ribosome
LB	0005840	cellular_component	ribosome
LB	0006412	biological_process	translation
LB	0015934	cellular_component	large ribosomal subunit
LC	0003723	molecular_function	RNA binding
LC	0003735	molecular_function	structural constituent of ribosome
LC	0005840	cellular_component	ribosome
LC	0006412	biological_process	translation
LC	0022625	cellular_component	cytosolic large ribosomal subunit
LC	0046872	molecular_function	metal ion binding
LC	1990904	cellular_component	ribonucleoprotein complex
LD	0003735	molecular_function	structural constituent of ribosome
LD	0005840	cellular_component	ribosome
LD	0006412	biological_process	translation
LE	0003723	molecular_function	RNA binding
LE	0003735	molecular_function	structural constituent of ribosome
LE	0005840	cellular_component	ribosome
LE	0006412	biological_process	translation
LE	0022625	cellular_component	cytosolic large ribosomal subunit
LE	1990904	cellular_component	ribonucleoprotein complex
LF	0003735	molecular_function	structural constituent of ribosome
LF	0005840	cellular_component	ribosome
LF	0006412	biological_process	translation
LF	0019843	molecular_function	rRNA binding
LG	0003735	molecular_function	structural constituent of ribosome
LG	0005840	cellular_component	ribosome
LG	0006412	biological_process	translation
LG	1990904	cellular_component	ribonucleoprotein complex
LH	0003723	molecular_function	RNA binding
LH	0042254	biological_process	ribosome biogenesis
LH	1990904	cellular_component	ribonucleoprotein complex
LI	0003735	molecular_function	structural constituent of ribosome
LI	0005840	cellular_component	ribosome
LI	0006412	biological_process	translation
LJ	0003735	molecular_function	structural constituent of ribosome
LJ	0005840	cellular_component	ribosome
LJ	0006412	biological_process	translation
LK	0003729	molecular_function	mRNA binding
LK	0003735	molecular_function	structural constituent of ribosome
LK	0005840	cellular_component	ribosome
LK	0006412	biological_process	translation
LK	0015934	cellular_component	large ribosomal subunit
LK	0017148	biological_process	negative regulation of translation
LK	0022625	cellular_component	cytosolic large ribosomal subunit
LK	1990904	cellular_component	ribonucleoprotein complex
LM	0003735	molecular_function	structural constituent of ribosome
LM	0005840	cellular_component	ribosome
LM	0006412	biological_process	translation
LM	0022625	cellular_component	cytosolic large ribosomal subunit
LM	0046872	molecular_function	metal ion binding
LM	0070180	molecular_function	large ribosomal subunit rRNA binding
LM	1990904	cellular_component	ribonucleoprotein complex
LN	0003723	molecular_function	RNA binding
LN	0003735	molecular_function	structural constituent of ribosome
LN	0005840	cellular_component	ribosome
LN	0006412	biological_process	translation
LO	0003735	molecular_function	structural constituent of ribosome
LO	0005840	cellular_component	ribosome
LO	0006412	biological_process	translation
LO	0015934	cellular_component	large ribosomal subunit
LP	0003735	molecular_function	structural constituent of ribosome
LP	0005840	cellular_component	ribosome
LP	0006412	biological_process	translation
LQ	0003735	molecular_function	structural constituent of ribosome
LQ	0005840	cellular_component	ribosome
LQ	0006412	biological_process	translation
LQ	0008097	molecular_function	5S rRNA binding
LR	0003735	molecular_function	structural constituent of ribosome
LR	0005840	cellular_component	ribosome
LR	0006412	biological_process	translation
LS	0003735	molecular_function	structural constituent of ribosome
LS	0005840	cellular_component	ribosome
LS	0006412	biological_process	translation
LT	0003723	molecular_function	RNA binding
LT	0003735	molecular_function	structural constituent of ribosome
LT	0005840	cellular_component	ribosome
LT	0006412	biological_process	translation
LT	0022625	cellular_component	cytosolic large ribosomal subunit
LT	1990904	cellular_component	ribonucleoprotein complex
LU	0003735	molecular_function	structural constituent of ribosome
LU	0005840	cellular_component	ribosome
LU	0006412	biological_process	translation
LV	0003735	molecular_function	structural constituent of ribosome
LV	0005840	cellular_component	ribosome
LV	0006412	biological_process	translation
LV	0015934	cellular_component	large ribosomal subunit
LW	0003735	molecular_function	structural constituent of ribosome
LW	0005840	cellular_component	ribosome
LW	0006412	biological_process	translation
LX	0003735	molecular_function	structural constituent of ribosome
LX	0005840	cellular_component	ribosome
LX	0006412	biological_process	translation
LX	0019843	molecular_function	rRNA binding
LY	0003723	molecular_function	RNA binding
LY	0003735	molecular_function	structural constituent of ribosome
LY	0005840	cellular_component	ribosome
LY	0006412	biological_process	translation
LY	0015934	cellular_component	large ribosomal subunit
LZ	0003735	molecular_function	structural constituent of ribosome
La	0003735	molecular_function	structural constituent of ribosome
La	0005840	cellular_component	ribosome
La	0006412	biological_process	translation
Lb	0003735	molecular_function	structural constituent of ribosome
Lb	0005840	cellular_component	ribosome
Lb	0006412	biological_process	translation
Lc	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Lc	0003729	molecular_function	mRNA binding
Lc	0003735	molecular_function	structural constituent of ribosome
Lc	0005840	cellular_component	ribosome
Lc	0006412	biological_process	translation
Lc	0022625	cellular_component	cytosolic large ribosomal subunit
Lc	1990904	cellular_component	ribonucleoprotein complex
Le	0003723	molecular_function	RNA binding
Le	0005840	cellular_component	ribosome
Le	1990904	cellular_component	ribonucleoprotein complex
Lf	0003723	molecular_function	RNA binding
Lf	0003735	molecular_function	structural constituent of ribosome
Lf	0005840	cellular_component	ribosome
Lf	0022625	cellular_component	cytosolic large ribosomal subunit
Lf	1990904	cellular_component	ribonucleoprotein complex
Lg	0003735	molecular_function	structural constituent of ribosome
Lg	0005840	cellular_component	ribosome
Lg	0006412	biological_process	translation
Lh	0003735	molecular_function	structural constituent of ribosome
Lh	0005840	cellular_component	ribosome
Lh	0006412	biological_process	translation
Li	0003735	molecular_function	structural constituent of ribosome
Li	0005840	cellular_component	ribosome
Li	0006412	biological_process	translation
Li	1990904	cellular_component	ribonucleoprotein complex
Lj	0003735	molecular_function	structural constituent of ribosome
Lj	0005840	cellular_component	ribosome
Lj	0006412	biological_process	translation
Lk	0003735	molecular_function	structural constituent of ribosome
Lk	0005840	cellular_component	ribosome
Lk	0006412	biological_process	translation
Ll	0003735	molecular_function	structural constituent of ribosome
Ll	0005840	cellular_component	ribosome
Ll	0006412	biological_process	translation
Lm	0003735	molecular_function	structural constituent of ribosome
Lm	0005840	cellular_component	ribosome
Lm	0006412	biological_process	translation
Lm	0008270	molecular_function	zinc ion binding
Lm	0046872	molecular_function	metal ion binding
Lm	1990904	cellular_component	ribonucleoprotein complex
Ln	0003735	molecular_function	structural constituent of ribosome
Ln	0005840	cellular_component	ribosome
Ln	0006412	biological_process	translation
Lo	0002181	biological_process	cytoplasmic translation
Lo	0003735	molecular_function	structural constituent of ribosome
Lo	0005840	cellular_component	ribosome
Lo	0006412	biological_process	translation
Lo	0022625	cellular_component	cytosolic large ribosomal subunit
Lo	1990904	cellular_component	ribonucleoprotein complex
Lp	0003735	molecular_function	structural constituent of ribosome
Lp	0005840	cellular_component	ribosome
Lp	0006412	biological_process	translation
Lq	0003735	molecular_function	structural constituent of ribosome
Lq	0005840	cellular_component	ribosome
Lq	0006412	biological_process	translation
Lr	0003735	molecular_function	structural constituent of ribosome
Lr	0005840	cellular_component	ribosome
Lr	0006412	biological_process	translation
Lv	0002182	biological_process	cytoplasmic translational elongation
Lv	0003735	molecular_function	structural constituent of ribosome
Lv	0022625	cellular_component	cytosolic large ribosomal subunit
Lw	0002182	biological_process	cytoplasmic translational elongation
Lw	0003735	molecular_function	structural constituent of ribosome
Lw	0022625	cellular_component	cytosolic large ribosomal subunit
SA	0003735	molecular_function	structural constituent of ribosome
SA	0005840	cellular_component	ribosome
SA	0006412	biological_process	translation
SA	0015935	cellular_component	small ribosomal subunit
SB	0003723	molecular_function	RNA binding
SB	0003735	molecular_function	structural constituent of ribosome
SB	0005840	cellular_component	ribosome
SB	0006412	biological_process	translation
SB	0015935	cellular_component	small ribosomal subunit
SB	0022626	cellular_component	cytosolic ribosome
SB	1990904	cellular_component	ribonucleoprotein complex
SC	0003723	molecular_function	RNA binding
SC	0003735	molecular_function	structural constituent of ribosome
SC	0006412	biological_process	translation
SC	0015935	cellular_component	small ribosomal subunit
SC	0019843	molecular_function	rRNA binding
SD	0003723	molecular_function	RNA binding
SD	0003735	molecular_function	structural constituent of ribosome
SD	0005840	cellular_component	ribosome
SD	0006412	biological_process	translation
SE	0003723	molecular_function	RNA binding
SE	0003735	molecular_function	structural constituent of ribosome
SE	0005840	cellular_component	ribosome
SE	0006412	biological_process	translation
SE	0015935	cellular_component	small ribosomal subunit
SF	0003723	molecular_function	RNA binding
SF	0003735	molecular_function	structural constituent of ribosome
SF	0006412	biological_process	translation
SF	0015935	cellular_component	small ribosomal subunit
SH	0003735	molecular_function	structural constituent of ribosome
SH	0005840	cellular_component	ribosome
SH	0006412	biological_process	translation
SI	0003735	molecular_function	structural constituent of ribosome
SI	0005840	cellular_component	ribosome
SI	0006412	biological_process	translation
SJ	0003723	molecular_function	RNA binding
SJ	0003735	molecular_function	structural constituent of ribosome
SJ	0005840	cellular_component	ribosome
SJ	0006412	biological_process	translation
SJ	0015935	cellular_component	small ribosomal subunit
SK	0003735	molecular_function	structural constituent of ribosome
SK	0005840	cellular_component	ribosome
SK	0006412	biological_process	translation
SL	0003735	molecular_function	structural constituent of ribosome
SL	0005840	cellular_component	ribosome
SL	0006412	biological_process	translation
SL	0015935	cellular_component	small ribosomal subunit
SM	0003676	molecular_function	nucleic acid binding
SM	0003723	molecular_function	RNA binding
SM	0003735	molecular_function	structural constituent of ribosome
SM	0005840	cellular_component	ribosome
SM	0006412	biological_process	translation
SN	0003735	molecular_function	structural constituent of ribosome
SN	0005840	cellular_component	ribosome
SN	0006412	biological_process	translation
SN	0008270	molecular_function	zinc ion binding
SO	0003735	molecular_function	structural constituent of ribosome
SO	0005840	cellular_component	ribosome
SO	0006412	biological_process	translation
SP	0003735	molecular_function	structural constituent of ribosome
SP	0005840	cellular_component	ribosome
SP	0006412	biological_process	translation
SQ	0003735	molecular_function	structural constituent of ribosome
SQ	0005840	cellular_component	ribosome
SQ	0006412	biological_process	translation
SR	0003723	molecular_function	RNA binding
SR	0003735	molecular_function	structural constituent of ribosome
SR	0005840	cellular_component	ribosome
SR	0006412	biological_process	translation
SR	0015935	cellular_component	small ribosomal subunit
SS	0003735	molecular_function	structural constituent of ribosome
SS	0005840	cellular_component	ribosome
SS	0006412	biological_process	translation
ST	0003735	molecular_function	structural constituent of ribosome
ST	0005840	cellular_component	ribosome
ST	0006412	biological_process	translation
SU	0003735	molecular_function	structural constituent of ribosome
SU	0005840	cellular_component	ribosome
SU	0006412	biological_process	translation
SX	0003735	molecular_function	structural constituent of ribosome
SX	0005840	cellular_component	ribosome
SX	0006412	biological_process	translation
SY	0003735	molecular_function	structural constituent of ribosome
SY	0005840	cellular_component	ribosome
SY	0006412	biological_process	translation
SZ	0003735	molecular_function	structural constituent of ribosome
SZ	0005840	cellular_component	ribosome
SZ	0006412	biological_process	translation
Sa	0005886	cellular_component	plasma membrane
Sa	0007165	biological_process	signal transduction

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVIVrqrkpwrrk.DGvfmyFedNagVI

Chain	Residue	Details
LM	ALA79-ILE105

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVKLTpdydaldV

Chain	Residue	Details
LX	LYS130-VAL145

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. RTdntIryNakrRHWRR

Chain	Residue	Details
Lo	ARG30-ARG46

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmhgrnnGKKimavrIVkhA

Chain	Residue	Details
SF	GLU66-ALA92

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyiVLTTSaGIMdheeAR

Chain	Residue	Details
SH	GLY100-ARG117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPvPTD

Chain	Residue	Details
SK	LEU115-ASP137

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
SL	LYS59-ARG66

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLAEFsiS

Chain	Residue	Details
SR	ASN107-SER131

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLSGQspVfSkARyT

Chain	Residue	Details
LE	LEU39-THR55

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGktSQiyAirqAiAKAL

Chain	Residue	Details
SI	GLY77-LEU95

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkdkSLkvkGPVrMPT

Chain	Residue	Details
SJ	ALA52-THR67

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. IrkHLernRkDkdSkfrLilVesrihrLarY

Chain	Residue	Details
SO	ILE98-TYR128

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIELiL

Chain	Residue	Details
LV	ARG127-LEU151

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PkvRGVAmNPvE

Chain	Residue	Details
LB	PRO197-GLU208

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FqkdemvDiiGvTkGKGyeGvvtR

Chain	Residue	Details
LC	PHE212-ARG235

site_id	PS00475
Number of Residues	33
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGmLpperpIvVkaklISkvAekkIkaaG

Chain	Residue	Details
LO	LYS105-GLY137

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlkCGkgkVWLDP

Chain	Residue	Details
LT	GLN7-PRO26

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKStGFGlIYDNldaakkyE

Chain	Residue	Details
SU	PHE70-GLU92

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfkdGyMisSgqpVneyIDaavrhvlLrqGvlG

Chain	Residue	Details
SB	ALA147-GLY183

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvVVGDnn.GhVGlGvkcak.EVat.AI

Chain	Residue	Details
SE	GLY102-ILE134

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PphfcksSgaIsRnILQqLQ

Chain	Residue	Details
SS	PRO92-GLN111

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LArRLqtlVFKagmAkSihhARvLI

Chain	Residue	Details
SC	LEU107-ILE131

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. ILqlLrLrQifNgVflkvnkatinMLrrVepYV

Chain	Residue	Details
Le	ILE104-VAL136

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHywGvrVRGQ

Chain	Residue	Details
SM	ARG121-GLN134

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IVSAsqDgRLIVWNA

Chain	Residue	Details
Sa	ILE81-ALA95
Sa	LEU173-VAL187
Sa	LEU313-THR327

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QkchVknKdiRkFlDGIYVsdK

Chain	Residue	Details
LF	GLN162-LYS183

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkytlGyKtvLKtlRsSlgKlIIL

Chain	Residue	Details
Lf	SER24-LEU48

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. IRGMIPhktarGEaalarLkAYeG

Chain	Residue	Details
LK	ILE89-GLY112

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NvhlRrvAVaSALaATSvpslvlaRGH

Chain	Residue	Details
LD	ASN120-HIS146

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLILtDprtDhqpIkEsalgNIP

Chain	Residue	Details
SA	PRO123-PRO147

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. DLGTacGKyyrvccLsIlDpG

Chain	Residue	Details
Lf	ASP80-GLY100

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
ST	LEU11-ALA19

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGqkIyPGkGirFiRaD

Chain	Residue	Details
LZ	PHE10-ASP27

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTgSfGkRrnkt.HtlCvRCG

Chain	Residue	Details
Ll	GLY4-GLY23

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmeVPYciVkGKarLG

Chain	Residue	Details
LH	CYS166-GLY183

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRpHGnsGvVrAkFrsnLP

Chain	Residue	Details
Lj	GLY73-PRO94

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSKtnRPpLSMrRL

Chain	Residue	Details
LR	LYS50-LEU67

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGsyKGre.GkV

Chain	Residue	Details
LY	ASP52-VAL69

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TkSnQtrvvKTPGG

Chain	Residue	Details
Li	THR15-GLY28

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCqgCfnittvFShSqtvvvCpgCQtvLcqPtG

Chain	Residue	Details
SX	LYS38-GLY70

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NgvPIRRvnqaYVIATSt.K

Chain	Residue	Details
LG	ASN113-LYS131

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GEhVdvkvngavhk.GmpHkfYhGrTG

Chain	Residue	Details
LU	GLY37-GLY62

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLKlqC

Chain	Residue	Details
Lr	LYS63-CYS74

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYEKRiTELLK

Chain	Residue	Details
Lk	PRO55-LYS65

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVVYRvRVrRG

Chain	Residue	Details
LP	ASP46-GLY69

site_id	PS01199
Number of Residues	20
Details	RIBOSOMAL_L1 Ribosomal protein L1 signature. IkqIprlLGpgLNKAGkFPT

Chain	Residue	Details
LA	ILE116-THR135

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtcARV

Chain	Residue	Details
LI	ALA108-VAL129

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)