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4V0W

The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-669)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000775cellular_componentchromosome, centromeric region
A0000776cellular_componentkinetochore
A0000781cellular_componentchromosome, telomeric region
A0001824biological_processblastocyst development
A0004721molecular_functionphosphoprotein phosphatase activity
A0004722molecular_functionprotein serine/threonine phosphatase activity
A0005515molecular_functionprotein binding
A0005521molecular_functionlamin binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005694cellular_componentchromosome
A0005730cellular_componentnucleolus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005741cellular_componentmitochondrial outer membrane
A0005815cellular_componentmicrotubule organizing center
A0005856cellular_componentcytoskeleton
A0005977biological_processglycogen metabolic process
A0006470biological_processprotein dephosphorylation
A0007283biological_processspermatogenesis
A0008157molecular_functionprotein phosphatase 1 binding
A0016607cellular_componentnuclear speck
A0016787molecular_functionhydrolase activity
A0016791molecular_functionphosphatase activity
A0017018molecular_functionmyosin phosphatase activity
A0019901molecular_functionprotein kinase binding
A0019903molecular_functionprotein phosphatase binding
A0019904molecular_functionprotein domain specific binding
A0030182biological_processneuron differentiation
A0030496cellular_componentmidbody
A0032154cellular_componentcleavage furrow
A0032922biological_processcircadian regulation of gene expression
A0032991cellular_componentprotein-containing complex
A0042752biological_processregulation of circadian rhythm
A0043153biological_processentrainment of circadian clock by photoperiod
A0043197cellular_componentdendritic spine
A0044877molecular_functionprotein-containing complex binding
A0046822biological_processregulation of nucleocytoplasmic transport
A0046872molecular_functionmetal ion binding
A0048511biological_processrhythmic process
A0051301biological_processcell division
A0060252biological_processpositive regulation of glial cell proliferation
A0072357cellular_componentPTW/PP1 phosphatase complex
A0098793cellular_componentpresynapse
A0098794cellular_componentpostsynapse
A0098978cellular_componentglutamatergic synapse
C0000775cellular_componentchromosome, centromeric region
C0000776cellular_componentkinetochore
C0000781cellular_componentchromosome, telomeric region
C0001824biological_processblastocyst development
C0004721molecular_functionphosphoprotein phosphatase activity
C0004722molecular_functionprotein serine/threonine phosphatase activity
C0005515molecular_functionprotein binding
C0005521molecular_functionlamin binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005694cellular_componentchromosome
C0005730cellular_componentnucleolus
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005741cellular_componentmitochondrial outer membrane
C0005815cellular_componentmicrotubule organizing center
C0005856cellular_componentcytoskeleton
C0005977biological_processglycogen metabolic process
C0006470biological_processprotein dephosphorylation
C0007283biological_processspermatogenesis
C0008157molecular_functionprotein phosphatase 1 binding
C0016607cellular_componentnuclear speck
C0016787molecular_functionhydrolase activity
C0016791molecular_functionphosphatase activity
C0017018molecular_functionmyosin phosphatase activity
C0019901molecular_functionprotein kinase binding
C0019903molecular_functionprotein phosphatase binding
C0019904molecular_functionprotein domain specific binding
C0030182biological_processneuron differentiation
C0030496cellular_componentmidbody
C0032154cellular_componentcleavage furrow
C0032922biological_processcircadian regulation of gene expression
C0032991cellular_componentprotein-containing complex
C0042752biological_processregulation of circadian rhythm
C0043153biological_processentrainment of circadian clock by photoperiod
C0043197cellular_componentdendritic spine
C0044877molecular_functionprotein-containing complex binding
C0046822biological_processregulation of nucleocytoplasmic transport
C0046872molecular_functionmetal ion binding
C0048511biological_processrhythmic process
C0051301biological_processcell division
C0060252biological_processpositive regulation of glial cell proliferation
C0072357cellular_componentPTW/PP1 phosphatase complex
C0098793cellular_componentpresynapse
C0098794cellular_componentpostsynapse
C0098978cellular_componentglutamatergic synapse
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MN A 301
ChainResidue
AASP64
AHIS66
AASP92
AMN303
AHOH2115

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MN A 303
ChainResidue
AMN301
AHOH2152
AASP92
AASN124
AHIS173
AHIS248

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MN C 301
ChainResidue
CASP64
CHIS66
CASP92
CMN303
CHOH2066

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MN C 303
ChainResidue
CASP92
CASN124
CHIS173
CHIS248
CMN301
CHOH2092

Functional Information from PROSITE/UniProt
site_idPS00125
Number of Residues6
DetailsSER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE
ChainResidueDetails
ALEU121-GLU126

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton donor => ECO:0000250
ChainResidueDetails
AHIS125
CHIS125

site_idSWS_FT_FI2
Number of Residues12
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP64
CASN124
CHIS173
CHIS248
AHIS66
AASP92
AASN124
AHIS173
AHIS248
CASP64
CHIS66
CASP92

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PDB entries from 2024-07-24

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