4UY4

1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007276	biological_process	gamete generation
B	0007276	biological_process	gamete generation

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1237

Chain	Residue
A	GLU65
A	VAL67
A	TYR149
A	ILE210
A	HIS211
A	PHE221

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	98
Details	Region: {"description":"Tudor-like domain 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Region: {"description":"Histone H3K4me3 and H3R8me2a binding","evidences":[{"source":"UniProtKB","id":"Q9Y657","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	90
Details	Region: {"description":"Tudor-like domain 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Site: {"description":"Histone H3K4me3 and H3R8me2a binding","evidences":[{"source":"UniProtKB","id":"Q9Y657","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	49
Details	Region: {"description":"Tudor-like domain 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Citrulline; alternate","evidences":[{"source":"PubMed","id":"16567635","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine; by HASPIN and VRK1","evidences":[{"source":"PubMed","id":"15681610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16185088","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31527692","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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