4UUZ
MCM2-histone complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000785 | cellular_component | chromatin |
| A | 0000786 | cellular_component | nucleosome |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005694 | cellular_component | chromosome |
| A | 0005700 | cellular_component | polytene chromosome |
| A | 0006334 | biological_process | nucleosome assembly |
| A | 0030527 | molecular_function | structural constituent of chromatin |
| A | 0031492 | molecular_function | nucleosomal DNA binding |
| A | 0035059 | cellular_component | RCAF complex |
| A | 0046982 | molecular_function | protein heterodimerization activity |
| B | 0000228 | cellular_component | nuclear chromosome |
| B | 0000786 | cellular_component | nucleosome |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005694 | cellular_component | chromosome |
| B | 0006334 | biological_process | nucleosome assembly |
| B | 0030527 | molecular_function | structural constituent of chromatin |
| B | 0035059 | cellular_component | RCAF complex |
| B | 0046982 | molecular_function | protein heterodimerization activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0006270 | biological_process | DNA replication initiation |
| C | 0042555 | cellular_component | MCM complex |
| C | 1905775 | biological_process | negative regulation of DNA helicase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00322 |
| Number of Residues | 7 |
| Details | HISTONE_H3_1 Histone H3 signature 1. KAPRKQL |
| Chain | Residue | Details |
| A | LYS14-LEU20 |
| site_id | PS00959 |
| Number of Residues | 9 |
| Details | HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI |
| Chain | Residue | Details |
| A | PRO66-ILE74 |
| site_id | PS00047 |
| Number of Residues | 5 |
| Details | HISTONE_H4 Histone H4 signature. GAKRH |
| Chain | Residue | Details |
| B | GLY14-HIS18 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by ATR => ECO:0000269|PubMed:15210935, ECO:0000269|PubMed:16899510, ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| C | SER108 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| C | TYR137 | |
| B | LYS12 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000269|PubMed:22389435 |
| Chain | Residue | Details |
| A | LYS37 | |
| B | LYS31 | |
| B | LYS77 | |
| B | LYS79 | |
| B | LYS91 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:18327897 |
| Chain | Residue | Details |
| B | THR80 | |
| B | THR82 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:14732680 |
| Chain | Residue | Details |
| A | LYS23 | |
| A | LYS18 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000269|PubMed:22389435 |
| Chain | Residue | Details |
| A | LYS56 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435 |
| Chain | Residue | Details |
| A | LYS79 |
