4UTT
Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006051 | biological_process | N-acetylmannosamine metabolic process |
| A | 0006053 | biological_process | N-acetylmannosamine catabolic process |
| A | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| A | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| A | 0047465 | molecular_function | N-acylglucosamine-6-phosphate 2-epimerase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006051 | biological_process | N-acetylmannosamine metabolic process |
| B | 0006053 | biological_process | N-acetylmannosamine catabolic process |
| B | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| B | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| B | 0047465 | molecular_function | N-acylglucosamine-6-phosphate 2-epimerase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006051 | biological_process | N-acetylmannosamine metabolic process |
| C | 0006053 | biological_process | N-acetylmannosamine catabolic process |
| C | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| C | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| C | 0047465 | molecular_function | N-acylglucosamine-6-phosphate 2-epimerase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006051 | biological_process | N-acetylmannosamine metabolic process |
| D | 0006053 | biological_process | N-acetylmannosamine catabolic process |
| D | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| D | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| D | 0047465 | molecular_function | N-acylglucosamine-6-phosphate 2-epimerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1221 |
| Chain | Residue |
| A | GLN14 |
| A | ARG43 |
| A | LYS66 |
| A | HOH2056 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1222 |
| Chain | Residue |
| A | ARG208 |
| A | PRO209 |
| A | GLN210 |
| A | HOH2073 |
| A | HOH2074 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1223 |
| Chain | Residue |
| A | LYS66 |
| A | TYR75 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 1221 |
| Chain | Residue |
| B | GLN14 |
| B | ARG43 |
| B | ILE64 |
| B | LYS66 |
| B | HOH2045 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 1222 |
| Chain | Residue |
| B | ARG208 |
| B | PRO209 |
| B | GLN210 |
| B | HOH2063 |
| B | HOH2065 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 1223 |
| Chain | Residue |
| B | LYS66 |
| B | TYR75 |
| B | THR147 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 1221 |
| Chain | Residue |
| C | GLN14 |
| C | ARG43 |
| C | LYS66 |
| C | HOH2052 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 1222 |
| Chain | Residue |
| C | ARG208 |
| C | PRO209 |
| C | GLN210 |
| C | HOH2068 |
| C | HOH2069 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT C 1223 |
| Chain | Residue |
| C | LYS66 |
| C | TYR75 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 1221 |
| Chain | Residue |
| D | GLN14 |
| D | ARG43 |
| D | LYS66 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1222 |
| Chain | Residue |
| D | ARG208 |
| D | PRO209 |
| D | GLN210 |
| D | HOH2061 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT D 1223 |
| Chain | Residue |
| D | LYS66 |
| D | TYR75 |
| D | HOH2009 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01235","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25320079","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01235","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25320079","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4UTU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25320079","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4UTW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
