Functional Information from GO Data
| Chain | GOid | namespace | contents |
| R | 0003924 | molecular_function | GTPase activity |
| R | 0005525 | molecular_function | GTP binding |
| R | 0007165 | biological_process | signal transduction |
| R | 0016020 | cellular_component | membrane |
| S | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| S | 0007264 | biological_process | small GTPase-mediated signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE RV1 R 1167 |
| Chain | Residue |
| R | LYS5 |
| S | HIS911 |
| S | TYR912 |
| R | LEU6 |
| R | ASP54 |
| R | LEU56 |
| R | TYR71 |
| R | THR74 |
| S | SER908 |
| S | GLU909 |
| S | ASP910 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE RV1 S 2046 |
| Chain | Residue |
| S | PRO759 |
| S | ILE782 |
| S | ARG786 |
| S | LEU865 |
| S | VAL1040 |
| S | ARG1041 |
| S | PRO1042 |
Functional Information from PROSITE/UniProt
| site_id | PS00720 |
| Number of Residues | 34 |
| Details | RASGEF Ras Guanine-nucleotide exchange factors domain signature. VPFfGiyLtNIlkteegnpevlkrhgkel.................INFsK |
| Chain | Residue | Details |
| S | VAL927-LYS960 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| R | GLY13 | |
| R | VAL29 | |
| R | ALA59 | |
| R | ASN116 | |
| R | SER145 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylmethionine; in GTPase HRas; alternate => ECO:0000269|Ref.12 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylthreonine; in GTPase HRas, N-terminally processed => ECO:0000269|Ref.12 |
| Chain | Residue | Details |
| R | CYS118 | |
| Chain | Residue | Details |
| R | THR35 | |
